MRI-Derived 3-D-Printed Breast Phantom for Microwave Breast Imaging Validation.

MRI-Derived 3-D-Printed Breast Phantom for Microwave Breast Imaging Validation.
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DOI:
10.1109/lawp.2012.2236293
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发表时间:
2012
影响因子:
4.2
通讯作者:
Hagness SC
Hagness SC
中科院分区:
计算机科学2区
文献类型:
--
作者:
Burfeindt MJ;Colgan TJ;Mays RO;Shea JD;Behdad N;Van Veen BD;Hagness SC

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我们提出了一个用于临床前实验微波成像研究的3d打印乳房假体。幻像来源于人体的核磁共振成像;因此,它是拟人化的,其内部与纤维腺组织的实际分布非常相似。乳房中的脂肪组织由假体的固体塑料(打印)区域表示,而纤维腺组织由塑料中充满液体的空隙表示。选择该液体以提供与印刷塑料具有生物学相关性的介电对比。这样的幻像可以验证微波成像技术。我们描述了生成3d打印乳房幻影的过程,并给出了在0.5-3.5 GHz频率范围内测量的3d打印塑料的介电特性。我们还提供了用于填充塑料纤维腺体空隙的合适液体的示例。
We propose a 3-D-printed breast phantom for use in preclinical experimental microwave imaging studies. The phantom is derived from an MRI of a human subject; thus, it is anthropomorphic, and its interior is very similar to an actual distribution of fibroglandular tissues. Adipose tissue in the breast is represented by the solid plastic (printed) regions of the phantom, while fibroglandular tissue is represented by liquid-filled voids in the plastic. The liquid is chosen to provide a biologically relevant dielectric contrast with the printed plastic. Such a phantom enables validation of microwave imaging techniques. We describe the procedure for generating the 3-D-printed breast phantom and present the measured dielectric properties of the 3-D-printed plastic over the frequency range 0.5–3.5 GHz. We also provide an example of a suitable liquid for filling the fibroglandular voids in the plastic.