Macroporous photopolymer frits for capillary electrochromatography
Macroporous photopolymer frits for capillary electrochromatography
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DOI：
10.1021/ac9911793
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发表时间：
2000-03-15
影响因子：
7.4
通讯作者：
Peters, E
中科院分区：
文献类型：
--
作者：
Chen, JR;Dulay, MT;Peters, E
通过甲基丙烯酸缩水甘油酯和三羟甲基丙烷三甲基丙烯酸酯溶液的紫外光聚合，在熔融石英毛细管中制备了大孔聚合物熔块。这种原位制备是一个简单、快速且可重复的过程。命中可以放置在沿列的任何所需位置。光聚合物击打可以承受短时间暴露于高压（超过 6000 psi）。在我们的实验条件下，没有观察到这些玻璃料出现气泡形成。通过选择致孔剂，可以控制多孔性质。在毛细管中使用此类玻璃料来保留色谱填料的颗粒已被证明在连续运行超过 3 天的情况下是稳定和稳健的。
Macroporous polymer frits have been fabricated in fused-silica capillaries by the UV photopolymerization of a solution of glycidyl methacrylate and trimethylolpropane trimethacrylate. This in situ preparation is a simple, rapid, and reproducible process. The hit can be placed at any desired position along the column. Photopolymer hits can withstand the short exposure to a high pressure (over 6000 psi). Bubble formation is not observed to occur with these frits under our experimental conditions. By choice of porogens, it is possible to control the porous properties. The use of such frits in capillaries to retain particles of chromatographic packing has been demonstrated to be stable and robust with continuous operation over 3 days.