Microbial transformation of benzosampangine.
Microbial transformation of benzosampangine.
复制标题
苯并桑葚碱的微生物转化。
DOI:
10.1021/np990493p
复制
发表时间:
2000
影响因子:
5.1
通讯作者:
Hufford,CD
中科院分区:
文献类型:
--
作者:
Orabi,KY;Clark,AM;Hufford,CD
Microbial transformation studies of the synthetic antifungal alkaloid benzosampangine (1) have revealed that1is metabolized by a number of microorganisms. Using a standard two-stage fermentation techniqueAbsidia glauca(ATCC 22752),Cunninghamella blakesleeana(ATCC 8688a),Cunninghamellaspecies (NRRL 5695),Fusarium solanif. sp.cucurbitae(CSIH #C-5), andRhizopogonspecies (ATCC 36060) each produced a β-glucopyranose conjugate of benzosampangine (2). The identity of2was established on the basis of spectroscopic data.