Chemical Characteristics of Salvia miltiorrhiza (Danshen) Collected from Different Locations in China
Chemical Characteristics of Salvia miltiorrhiza (Danshen) Collected from Different Locations in China
复制标题
DOI：
10.1021/jf901462s
复制
发表时间：
2009-08-12
影响因子：
6.1
通讯作者：
Li, Shao-Ping
中科院分区：
文献类型：
--
作者：
Zhong, Guo-Xin;Li, Peng;Li, Shao-Ping
对丹参（丹参）中的原儿茶酸、原儿茶醛、咖啡酸、阿魏酸、异阿魏酸、迷迭香酸、丹参素酸B、丹参素酸A、二氢丹参酮I、丹参素、隐丹参酮、丹参酮1和丹参酮IIA等13种亲水亲脂性化合物进行了同时定量分析，从不同地点采集的74个样品中，使用超高效液相色谱法（UPLC）。对13个化合物进行系统聚类分析，并结合整个色谱图的相似性，表明S。丹参与丹参的混淆品甘西丹参有显著性差异。对S.结果表明，丹参药材中丹参素B、迷迭香酸、隐丹参酮、丹参酮Ⅰ和Ⅱ A可作为丹参药材的质量评价指标。丹参，
The chemical characteristics of Salvia miltiorrhiza, also called "danshen" in China, were investigated on the basis of the simultaneous quantitative determination of 13 hydrophilic and lipophilic compounds, namely, protocatechuic acid, protocatechuic aldehyde, caffeic acid, ferulic acid, isoferulic acid, rosmarinic acid, salvianolic acid B, salvianolic acid A, dihydrotanshinone I, przewalskin, cryptotanshinone, tanshinone 1, and tanshinone IIA, in 74 samples collected from different locations using ultraperformance liquid chromatography (UPLC). Hierarchical clustering analysis based on 13 investigated compounds and the similarity of the entire chromatographic pattern showed that S. miltiorrhiza was significantly different from Salvia przewalskii, an adulterant of danshen. The chemical characteristics of S. miltiorrhiza collected from different locations in China were revealed, and salvianolic acid B, rosmarinic acid, cryptotanshinone, and tanshinones I and IIA were optimized as markers for the evaluation, which is helpful in the quality control of S. miltiorrhiza,