Phyllodes tumors of the breast: clinicopathological analysis of 106 cases from a single institution.

Phyllodes tumors of the breast: clinicopathological analysis of 106 cases from a single institution.
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DOI:
10.3233/bd-170297
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发表时间:
2018-01-01
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影响因子:
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通讯作者:
Fatemi, Hinde El
Fatemi, Hinde El
中科院分区:
其他
文献类型:
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作者:
Efared, Boubacar;Ebang, Gabrielle Atsame;Fatemi, Hinde El

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背景:叶状肿瘤(PT)是一种少见的双相肿瘤,占所有乳腺原发性肿瘤的不到1%。它们形成各种各样的肿瘤,从良性到恶性。几种组织学特征用于将PT分为3类:良性(I级)、交界性(II级)和恶性(III级)肿瘤。我们的研究目的是分析组织病理学,放射学和临床特征的PT从一个单一的center.METHODS经验:这是一项回顾性研究,包括106例患者诊断为叶状肿瘤的手术标本在病理科,哈桑II大学医院(非斯,摩洛哥),从2009年到2016年。平均年龄33.81岁年龄13-66岁,平均年龄随肿瘤分级而增加(I、II和III级PT的平均年龄分别为32.32、32.87和33.65岁)良性PT 78例(73.58%),交界性PT 20例(18.86%),恶性PT 8例(7.54%)。大多数情况下,肿瘤大小
BACKGROUND: Phyllodes tumors (PT) are uncommon biphasic tumors, accounting for less than 1% of all breast primary neoplasms. They form a wide variety of tumors ranging from benign to malignant. Several histological features are used to grade PT into 3 categories: benign (gradeI), borderline (gradeII) and malignant (gradeIII) tumors. The aim of our study was to analyse histolopathological, radiological and clinical features of PT from an experience of a single center.METHODS: It was a retrospective study including 106 patients diagnosed with phyllodes tumors on surgical specimens at the department of pathology, of Hassan II university hospital (Fez, Morocco), from 2009 to 2016.RESULTS: The mean age was 33.81 years (range of 13-66years), and the mean age increases with the tumor grade (mean ages of 32.32, 32.87 and 33.65 years respectively for grade I, II and III PT) (p = 0.023); 78 patients (73.58%) had benign PT, 20 (18.86%) had borderline PT and 8 (7.54%) patients were diagnosed with malignant PT. Mostly, the tumor size was