Phyllodes tumors of the breast: clinicopathological analysis of 106 cases from a single institution.
Phyllodes tumors of the breast: clinicopathological analysis of 106 cases from a single institution.
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DOI:
10.3233/bd-170297
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发表时间:
2018-01-01
期刊:
影响因子:
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通讯作者:
Fatemi, Hinde El
中科院分区:
文献类型:
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作者:
Efared, Boubacar;Ebang, Gabrielle Atsame;Fatemi, Hinde El
BACKGROUND: Phyllodes tumors (PT) are uncommon biphasic tumors, accounting for less than 1% of all breast primary neoplasms. They form a wide variety of tumors ranging from benign to malignant. Several histological features are used to grade PT into 3 categories: benign (gradeI), borderline (gradeII) and malignant (gradeIII) tumors. The aim of our study was to analyse histolopathological, radiological and clinical features of PT from an experience of a single center.METHODS: It was a retrospective study including 106 patients diagnosed with phyllodes tumors on surgical specimens at the department of pathology, of Hassan II university hospital (Fez, Morocco), from 2009 to 2016.RESULTS: The mean age was 33.81 years (range of 13-66years), and the mean age increases with the tumor grade (mean ages of 32.32, 32.87 and 33.65 years respectively for grade I, II and III PT) (p = 0.023); 78 patients (73.58%) had benign PT, 20 (18.86%) had borderline PT and 8 (7.54%) patients were diagnosed with malignant PT. Mostly, the tumor size was