The longitudinal association between homelessness, injection drug use, and injection-related risk behavior among persons with a history of injection drug use in Baltimore, MD
The longitudinal association between homelessness, injection drug use, and injection-related risk behavior among persons with a history of injection drug use in Baltimore, MD
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DOI：
10.1016/j.drugalcdep.2013.03.009
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发表时间：
2013-10-01
影响因子：
4.2
通讯作者：
Mehta, Shruti H.
中科院分区：
文献类型：
--
作者：
Linton, Sabriya L.;Celentano, David D.;Mehta, Shruti H.
背景资料：很少有研究评估无家可归和注射毒品使用之间的时间关联，以及注射相关的风险行为。在2005年至2009年随访的1405名现任和前任注射吸毒者中，我们使用随机截距模型评估无家可归与随后注射吸毒之间的时间关联，并确定在活跃注射者中无家可归与持续注射毒品之间的关联是否不同于停止注射者中无家可归与复发之间的关联。我们还评估了在两次访问中连续注射药物的参与者中无家可归与随后注射相关风险行为之间的关联。无家可归者被分类的持续时间：没有，= 1 months.Results：无家可归者报告至少有一次由532（38%）的参与者。无家可归与随后注射吸毒之间的关系对于活跃的注射者和停止注射者是不同的。在那些停止注射的人中，无家可归与复发相关[= 1个月：AOR =1.34 95%CI（0.77，2.33）]。在活跃的注射者中，无家可归与持续注射毒品使用无关[= 1个月：AOR= 0.81 95% CI（0.56，1.17）]。在连续两次注射毒品的人群中，无家可归时间≥ 1个月者与随后的注射相关危险行为相关[AOR = 1.61，95%CI（1.06，2.45）]。加强防止无家可归的政策和干预措施可以减少注射毒品使用和与注射有关的风险行为。(C)2013爱思唯尔爱尔兰有限公司版权所有。
Background: Few studies have assessed the temporal association between homelessness and injection drug use, and injection-related risk behavior.Methods: Among a cohort of 1405 current and former injection drug users in follow-up from 2005 to 2009, we used random intercept models to assess the temporal association between homelessness and subsequent injection drug use, and to determine whether the association between homelessness and sustained injection drug use among active injectors differed from the association between homelessness and relapse among those who stopped injecting. We also assessed the association between homelessness and subsequent injection-related risk behavior among participants who injected drugs consecutively across two visits. Homelessness was categorized by duration: none, = 1 month.Results: Homelessness was reported on at least one occasion by 532 (38%) participants. The relationship between homelessness and subsequent injection drug use was different for active injectors and those who stopped injecting. Among those who stopped injecting, homelessness was associated with relapse [= 1 month: AOR =1.34 95% Cl (0.77,2.33)]. Among active injectors, homelessness was not associated with sustained injection drug use [= 1 month: AOR= 0.81 95% CI (0.56, 1.17)]. Among those injecting drugs across two consecutive visits, homelessness >= 1 month was associated with subsequent injection-related risk behavior [AOR =1.61, 95% CI (1.06, 2.45)].Conclusion: Homelessness appears to be associated with relapse and injection-related risk behavior. Strengthening policies and interventions that prevent homelessness may reduce injection drug use and injection-related risk behaviors. (C) 2013 Elsevier Ireland Ltd. All rights reserved.