FDG-PET/CT imaging biomarkers in head and neck squamous cell carcinoma.
FDG-PET/CT imaging biomarkers in head and neck squamous cell carcinoma.
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DOI：
10.2217/iim.12.60
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发表时间：
2012-12
期刊：
影响因子：
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通讯作者：
Subramaniam RM
中科院分区：
文献类型：
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作者：
Paidpally V;Chirindel A;Lam S;Agrawal N;Quon H;Subramaniam RM
本文讨论18f -氟-2-脱氧葡萄糖PET/CT成像生物标志物在头颈部鳞状细胞癌中的价值。18f -氟-2-脱氧葡萄糖PET/CT在基线分期、放疗计划、治疗反应评估和头颈部鳞状细胞癌患者随访中具有重要价值。最大和峰值标准化摄取值（SUVmax和SUVpeak）、代谢肿瘤体积和病变总糖酵解是研究中常见的18f -氟-2-脱氧葡萄糖定量参数，以及定性评估。这些参数将根据其作为患者风险分层、治疗反应和生存结果的非侵入性生物标志物的既定或潜在作用进行评估。
This article discusses the value of 18F-fluoro-2-deoxyglucose PET/CT imaging biomarkers in head and neck squamous cell carcinoma. 18F-fluoro-2-deoxyglucose PET/CT is valuable at baseline staging, radiotherapy planning, therapy response assessment and in the follow-up of patients with head and neck squamous cell carcinoma. Maximum and peak standardized uptake value (SUVmax and SUVpeak), metabolic tumor volume and total lesion glycolysis are the common 18F-fluoro-2-deoxyglucose quantitative parameters that have been studied, along with qualitative assessments. These parameters will be evaluated with respect to their established or potential role as noninvasive biomarkers for patient risk stratification, treatment response and survival outcome.