Longitudinal Association between Animal and Vegetable Protein Intake and Obesity among Men in the United States: The Chicago Western Electric Study
Longitudinal Association between Animal and Vegetable Protein Intake and Obesity among Men in the United States: The Chicago Western Electric Study
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DOI：
10.1016/j.jada.2011.05.002
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发表时间：
2011-08-01
影响因子：
--
通讯作者：
Stamler, Jeremiah
中科院分区：
文献类型：
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作者：
Bujnowski, Deborah;Xun, Pengcheng;Stamler, Jeremiah
背景 关于蛋白质摄入量与体重之间关系的文献并不一致。人们对长期蛋白质摄入量与肥胖之间的关系知之甚少。目的本研究旨在确定蛋白质摄入量与肥胖之间的关联。设计从1958年到1966年，对芝加哥西电研究中1,730名年龄在40到55岁之间的白人男性进行了跟踪调查。在两次基线检查中，采用伯克综合饮食史方法对饮食进行了两次评估；每年由训练有素的访谈员测量身高、体重和其他协变量。使用广义估计方程来检验基线总蛋白、动物蛋白和植物蛋白摄入量与连续年度检查中超重或肥胖的可能性之间的关系。结果在 7 年的随访中，膳食动物蛋白与超重和肥胖呈正相关。调整潜在混杂因素（年龄、教育程度、吸烟、饮酒、能量、碳水化合物和饱和脂肪摄入量以及糖尿病或其他慢性疾病史）后，肥胖的比值比（95% 置信区间）为 4.62（2.68 至 7.98）（P 为趋势）
Background Literature on the association of protein intake with body weight is inconsistent. Little is known about the relation of long-term protein intake to obesity.Objective This study aimed to determine the association between protein intake and obesity.Design A cohort of 1,730 employed white men aged 40 to 55 years from the Chicago Western Electric Study was followed from 1958 to 1966. Diet was assessed twice with Burke's comprehensive diet history method at two baseline examinations; height, weight, and other covariates were measured annually by trained interviewers. Generalized estimating equation was used to examine the relation of baseline total, animal, and vegetable protein intake to likelihood of being overweight or obese at sequential annual examinations.Results Dietary animal protein was positively related to overweight and obesity across 7 years of follow up. With adjustment for potential confounders (age, education, cigarette smoking, alcohol intake, energy, carbohydrate and saturated fat intake, and history of diabetes or other chronic disease), the odds ratios (95% confidence intervals) for obesity were 4.62 (2.68 to 7.98) (P for trend