Comparison of Young Adult Female Cancer Survivors Recruited from a Population-Based Cancer Registry to Eligible Survivors.
Comparison of Young Adult Female Cancer Survivors Recruited from a Population-Based Cancer Registry to Eligible Survivors.
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DOI：
10.1158/1055-9965.epi-20-1409
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发表时间：
2021-04
期刊：
影响因子：
--
通讯作者：
Mertens AC
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文献类型：
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作者：
Howards PP;Mink PJ;Kim KH;Woodard JJ;Mertens AC
以人群为基础的癌症登记提供了一种资源来招募年轻的成年癌症幸存者，否则他们可能不容易被发现。我们比较了女性年轻成年癌症幸存者队列参与者的人口统计学和癌症相关特征，以及乔治亚州癌症登记处（美国基于人口的登记处）中符合条件的幸存者。我们使用逻辑回归检验了幸存者特征与不参与之间的关联，并使用多元回归检验了幸存者特征与不同类型的不参与（拒绝、无法联系或未解决与访谈）之间的关联。乔治亚州癌症登记处能够联系到60%的符合条件的妇女（3,061/5,137）。其中，78%的人同意研究接触（n= 2378），其中56%的人接受了采访（n= 1342）。接触时和诊断时的年龄参与情况相似，但癌症类型不同，从宫颈癌的17%到乳腺癌的32%不等。白人女性接受采访的可能性（28%）略高于非裔美国女性（23%），这主要是由于与非裔美国女性接触更困难（优势比为1.7,95%置信区间为1.5,2.1）。招募女性的最大挑战是与她们联系，这在人口统计学和癌症相关特征方面存在一些差异，但不是全部。成功联系上后，大多数幸存者都同意参与。以人群为基础的癌症登记可以作为一种宝贵的资源，以招募具有代表性的年轻成年癌症幸存者样本，否则很难识别。
Population-based cancer registries provide a resource to recruit young adult cancer survivors who may not be easily identified otherwise. We compared demographic and cancer-related characteristics of participants in a cohort of female young adult cancer survivors to those of eligible survivors in the Georgia Cancer Registry, a population-based registry in the United States. We examined associations between survivor characteristics and non-participation using logistic regression and associations between survivor characteristics and different types of non-participation (refusal, unable to contact, or unresolved vs. interviewed) using polytomous regression. The Georgia Cancer Registry was able to contact 60% of eligible women (3,061/5,137). Of those, 78% agreed to study contact (n=2,378), and of those, 56% were interviewed (n=1,342). Participation was similar across age at contact and at diagnosis but varied across cancer type from 17% for cervical cancer to 32% for breast cancer. White women were slightly more likely to be interviewed (28%) than African-American women (23%), which was mostly attributable to greater difficulty in contacting African-American women (odds ratio 1.7, 95% confidence interval: 1.5, 2.1). The greatest challenge to recruiting women was contacting them, which differed across some but not all demographic and cancer-related characteristics. When successfully contacted, most survivors agreed to participate. Population-based cancer registries can serve as an invaluable resource to recruit representative samples of young adult cancer survivors, who are otherwise difficult to identify.