Enantioselective hydrogenation of acetophenone by (1S, 2S)-DPEN–Ru(II)Cl2(PPh3)2 encapsulated in Al-MCM-41
Enantioselective hydrogenation of acetophenone by (1S, 2S)-DPEN–Ru(II)Cl2(PPh3)2 encapsulated in Al-MCM-41
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DOI：
10.1016/j.cclet.2010.03.011
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发表时间：
2010-07
影响因子：
9.1
通讯作者：
Jian Hong Liu;D. Liang;B. Fan;Ruifeng Li;Hua Chen
中科院分区：
文献类型：
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作者：
Jian Hong Liu;D. Liang;B. Fan;Ruifeng Li;Hua Chen
通过静电吸附和1，1-二氯硅环丁烷修饰，将手性Ru配合物[1S，2S)-DPEN]–RuCl2(PPh3)2(DPEN=1，2-diphenylethylenediamine，PPh_3=三苯基膦]包埋在Al-MCM-41分子筛的孔道中。制备的多相催化剂在苯乙酮的不对称加氢反应中表现出与相应均相催化剂相同的催化活性和对映体选择性，并且可以重复使用至少7次而不会有明显的催化活性和对映体选择性损失。
A chiral ruthenium complex [(1S, 2S)-DPEN]–RuCl2(PPh3)2(DPEN=1,2-diphenylethylenediamine, PPh3=triphenylphosph-ine) was encapsulated in the channel of Al-MCM-41 by electrostatic adsorption and 1,1-dichlorosilacyclobutane modification. The prepared heterogeneous catalyst showed the same catalytic activity and enantioselectivity as the corresponding homogeneous catalyst in the asymmetric hydrogenation of acetophenone, and could be reused at least seven times without significant loss of catalytic activity and enantioselectivity.