SERUM APOLIPOPROTEIN LEVELS IN RELATION TO ACUTE MYOCARDIAL-INFARCTION AND ITS RISK-FACTORS - APOLIPOPROTEIN A-I LEVELS IN MALE SURVIVORS OF MYOCARDIAL-INFARCTION
SERUM APOLIPOPROTEIN LEVELS IN RELATION TO ACUTE MYOCARDIAL-INFARCTION AND ITS RISK-FACTORS - APOLIPOPROTEIN A-I LEVELS IN MALE SURVIVORS OF MYOCARDIAL-INFARCTION
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DOI：
10.1016/0021-9150(80)90199-9
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发表时间：
1980-01-01
期刊：
影响因子：
5.3
通讯作者：
BONDJERS, G
中科院分区：
文献类型：
--
作者：
FAGER, G;WIKLUND, O;BONDJERS, G
高密度脂蛋白在动脉粥样硬化临床并发症病因学中的重要性最近受到越来越多的关注。在急性心肌梗死患者中测定高密度脂蛋白中主要载脂蛋白 apo A-I 的水平，并与胆固醇匹配组和随机选择的对照组进行比较。患者中的 ApoA-I 水平低于对照组。吸烟者的 ApoA-I 水平低于不吸烟者。即使根据吸烟习惯对各组进行分层，患者组和对照组之间的差异仍然存在。即使考虑到已确定的危险因素——吸烟和高脂血症，低水平的apoA-I和α-脂蛋白胆固醇也是梗塞患者的附加特征。
The significance of high density lipoproteins in the etiology of clinical complications to atherosclerosis has recently received increased attention. The levels of the major apolipoprotein in high density lipoprotein, apo A-I were determined in patients who had an acute myocardial infarction and compared with a cholesterol-matched and a randomly selected control group. ApoA-I levels were lower in the patients than in the control groups. ApoA-I levels were lower in smokers than in non-smokers. The difference between patients and control groups persisted even when the groups were stratified according to smoking habits. Low levels of apoA-I and .alpha.-lipoprotein cholesterol are additional characteristics of the infarction patients even when the established risk factors, smoking and hyperlipidemia, are considered.