Use of the Hamilton and Montgomery-Asberg depression scales in institutionalized elderly patients
Use of the Hamilton and Montgomery-Asberg depression scales in institutionalized elderly patients
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DOI：
10.1097/00019442-199622430-00007
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发表时间：
1996-06-01
影响因子：
7.2
通讯作者：
DiFilippo, S
中科院分区：
文献类型：
--
作者：
Samuels, SC;Katz, IR;DiFilippo, S
在筛选重度抑郁症药物治疗研究的过程中，作者获得了老年住院患者抑郁症状的数据（N = 116，平均年龄84岁，81%为女性）。汉密尔顿抑郁评定量表的主成分分析（最大变量旋转）得出四因素解决方案（占方差的47.2%）：核心抑郁、焦虑、失眠疑病症和认知观念症状。蒙哥马利-阿斯伯格抑郁量表产生了两个因素（54%的方差）——核心抑郁和焦虑。两个量表的核心抑郁因素得分（但不包括其他因素得分）预测死亡率。在控制了疾病负担和残疾的测量后，核心抑郁与死亡率（在可获得这些协变量数据的患者亚组中）的关联仍然显著。
In screening for a study of drug treatment of major depression, the authors obtained data on depressive symptoms in elderly residential care patients (N = 116; average age 84 years; 81% women). Principal-components analysis (with varimax rotation) of the Hamilton Rating Scale for Depression yielded a four-factor solution (accounting for 47.2% of variance): core depression, anxiety, insomnia-hypochondriasis, and cognitive-ideational symptoms. The Montgomery-Asberg Depression Scale yielded two factors (54% of variance)-core depression and anxiety. Core depression factor scores from both scales (but not other factor scores) predicted mortality. The association of core depression with mortality (in subsets of patients for which data on these covariates were available) remained significant after measures of illness burden and disability were controlled.