Highlights of the First International "Immunotherapy in Pediatric Oncology: Progress and Challenges" Meeting.
Highlights of the First International "Immunotherapy in Pediatric Oncology: Progress and Challenges" Meeting.
复制标题
首届国际“小儿肿瘤免疫治疗：进展与挑战”会议亮点。
DOI：
10.1097/mph.0b013e31819a5d8d
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
Mackall,CrystalL
中科院分区：
文献类型：
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作者：
Capitini,ChristianM;Cooper,LaurenceJN;Egeler,RMaarten;Handgretinger,Rupert;Locatelli,Franco;Sondel,PaulM;Mackall,CrystalL
The first annual conference on immunotherapy in pediatric oncology was held in Bethesda, MD, from September 9 to 10, 2008 to discuss the state-of-the-art of immunotherapeutic strategies currently being explored in pediatric oncology. Major topics included targeting cell surface receptors, understanding and improving T-cell–based therapies, augmenting innate immune strategies, and enhancing graft-versus-leukemia for pediatric malignancies. As can be seen in the summaries of the individual presentations, significant progress has been made in developing preclinical models of pediatric tumors and a variety of novel immunobiologic therapies are approaching, or already in, the clinic. Although there is much excitement about the potential utility of these agents, a great deal of challenges lie ahead in improving the efficacy of each of these modalities and getting them to patients in a timely fashion. The resulting discussions will hopefully lead to new collaborations and insight for further translational and clinical studies.
