Use of buprenorphine for those with employer-sponsored insurance during the initial phase of the COVID-19 pandemic.
Use of buprenorphine for those with employer-sponsored insurance during the initial phase of the COVID-19 pandemic.
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DOI：
10.1016/j.jsat.2021.108384
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发表时间：
2021-10
影响因子：
3.9
通讯作者：
Whaley CM
中科院分区：
文献类型：
--
作者：
Cantor J;Dick AW;Haffajee R;Pera MF;Bravata DM;Stein BD;Whaley CM
量化那些拥有雇主保险的人每周使用丁丙诺啡的比率，以及该比率是否基于县级种族措施，历史致命药物过量率和COVID-19病例率而有所不同。我们使用了2020年私人保险人群中480万成年人的药品索赔，以检查2020年COVID-19大流行爆发期间丁丙诺啡治疗阿片类药物使用障碍的变化。我们根据2018年各县的致命药物过量率、人均COVID-19病例数和非白人百分比，通过检查各县使用率的变化来量化变化。在1月的第一周（每10，000名入组者中有0.6名，95%CI = 0.2至1.1）和8月的最后一周（每10，000名入组者中有0.8名，95%CI = 0.4至1.3）之间，丁丙诺啡的每周使用相对稳定。我们没有发现证据表明，截至2020年8月31日，县级县的COVID-19率、年龄调整的致命药物过量率和非白人百分比在丁丙诺啡使用方面发生了任何一致的变化。与县年龄调整的致命药物过量率最低的县相比，县年龄调整的致命药物过量率最高的县的使用率始终较高。我们的研究结果提供了早期证据，表明新的联邦和州一级的政策可能已经提高了大流行期间雇主保险的丁丙诺啡使用率。
To quantify weekly rates of use of buprenorphine for those with employer-based insurance and whether the rate differs based on county-level measures of race, historical fatal drug overdose rate, and COVID-19 case rate. We used 2020 pharmaceutical claims for 4.8 million adults from a privately insured population to examine changes in the use of buprenorphine to treat opioid use disorder in 2020 during the onset of the COVID-19 pandemic. We quantified variation by examining changes in use rates across counties based on their fatal drug overdose rate in 2018, number of COVID-19 cases per capita, and percent nonwhite. Weekly use of buprenorphine was relatively stable between the first week of January (0.6 per 10,000 enrollees, 95%CI = 0.2 to 1.1) and the last week of August (0.8 per 10,000 enrollees, 95%CI = 0.4 to 1.3). We did not find evidence of any consistent change in use of buprenorphine by county-level terciles for COVID-19 rate as of August 31, 2020, age-adjusted fatal drug overdose rate, and percent nonwhite. Use was consistently higher for counties in the highest tercile of county age-adjusted fatal drug overdose rate when compared to counties in the lowest tercile of county age-adjusted fatal drug overdose rate. Our results provide early evidence that new federal- and state-level policies may have steadied the rate of using buprenorphine for those with employer-based insurance during the pandemic.
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影响因子：
3.5
作者：
Stein, Bradley D.;Dick, Andrew W.;Pacula, Rosalie Liccardo
通讯作者：
Pacula, Rosalie Liccardo
影响因子：
13.8
作者：
Whaley CM;Pera MF;Cantor J;Chang J;Velasco J;Hagg HK;Sood N;Bravata DM
通讯作者：
Bravata DM
影响因子：
13.8
作者：
Haffajee, Rebecca L.;Lin, Lewei Allison;Goldstick, Jason E.
通讯作者：
Goldstick, Jason E.
影响因子：
24
作者：
Gluckman, Ty J.;Wilson, Michael A.;Spinelli, Kateri J.
通讯作者：
Spinelli, Kateri J.
影响因子：
33.9
作者：
Hartnett, Kathleen P.;Kite-Powell, Aaron;Gundlapalli, Adi, V
通讯作者：
Gundlapalli, Adi, V