Transcription and splicing When the twain meet

Transcription and splicing When the twain meet
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DOI:
10.4161/trns.2.5.17273
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发表时间:
2011-01-01
影响因子:
3.6
通讯作者:
Shav-Tal, Yaron
Shav-Tal, Yaron
中科院分区:
其他
文献类型:
--
作者:
Brody, Yehuda;Shav-Tal, Yaron

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剪接可以共转录方式发生。当剪接反应滞后于转录过程完成后会发生什么?我们发现,延伸率是独立的正在进行的剪接上检查的基因,并建议,当转录已完成,但剪接没有,剪接机器保留在转录的网站,独立的聚合酶。
Splicing can occur co-transcriptionally. What happens when the splicing reaction lags after the completed transcriptional process? We found that elongation rates are independent of ongoing splicing on the examined genes and suggest that when transcription has completed but splicing has not, the splicing machinery is retained at the site of transcription, independently of the polymerase.