Development of a non-invasive screening device of diabetic peripheral neuropathy based on the perception of micro-vibration
Development of a non-invasive screening device of diabetic peripheral neuropathy based on the perception of micro-vibration
复制标题
基于微振动感知的糖尿病周围神经病变无创筛查装置研制
DOI：
10.1109/cibcb.2016.7758107
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
Yu Nakamura
中科院分区：
文献类型：
--
作者：
H. Sawada;K. Uchida;J. Danjo;Yu Nakamura
据估计，2014年全球有4.2亿人患有糖尿病，自1980年以来已增加了四倍，预计到2025年这一数字将达到7亿。糖尿病是一组代谢性疾病，由于胰腺或新陈代谢的功能问题而导致人高血糖。糖尿病患者未经治疗，会因血管内的高血糖而受到损害，从而开始破坏毛细血管，降低触觉的敏感性，进而影响各个器官和神经系统。糖尿病周围神经病变是糖尿病的并发症之一，作者关注糖尿病早期触觉敏感性的下降。通过使用采用形状记忆合金丝的新型微振动执行器，我们开发了一种基于微振动模式感知的糖尿病水平非侵入性筛查装置。在医疗诊所进行实验，检查触觉刺激与糖尿病医学诊断之间的关系。
An estimated number of 420 million people in the world had diabetes mellitus in 2014, which had become quadruple since 1980, and the number is estimated to be 700 million by 2025. Diabetes mellitus is a group of metabolic diseases, which causes high blood sugar to a person, due to the functional problems of the pancreas or the metabolism. Patients of untreated diabetes would be damaged by the high blood sugar in vessels, and this starts to destroy capillary vessels to lower the sensitivity of tactile sensations, then effects to various organs and nerve systems. Diabetic peripheral neuropathy is one of the complications of diabetes mellitus, and the authors pay attention to the decline of the sensitivity of tactile sensations in the early stage of diabetes. By using a novel micro-vibration actuator that employs a shape-memory alloy wire, we develop a non-invasive screening device of the level of diabetes based on the perception of micro-vibration patterns. Experiments are conducted in a medical clinic, and the relation between the tactile stimuli and the medical diagnosis of diabetes are examined.