BAM: BioAmbient machine
BAM: BioAmbient machine
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BAM：BioAmbient 机器
DOI：
10.1109/acsd.2008.4574594
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发表时间：
2008
期刊：
影响因子：
--
通讯作者：
M. Vigliotti
中科院分区：
文献类型：
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作者：
Vinod A. Muganthan;Andrew Phillips;M. Vigliotti
近年来，越来越明显的是，为并发编程开发的技术实际上对于分析生物学中的复杂系统非常有用。在某种抽象层面上，可以将生物现象（例如基因转录、蛋白质相互作用和细胞间通信）视为根据化学反应规则进行计算的并发实体。在本文中，我们提出了一种用于表示和随机模拟具有移动隔室的复杂生物系统的工具。我们的工具 BAM 实现了 BioAmbient 演算的随机版本，有助于理解和推理生物调节网络中组件之间的多重互连。
In recent years it has become clear that techniques developed for concurrent programming are in fact very useful for the analysis of complex systems in biology. To some level of abstraction, it is possible to regard biological phenomena, such as gene transcription, protein interaction and communication among cells, as concurrent entities that compute according to the rules of chemical reactions. In this paper we present a tool for representing and stochastically simulating complex biological systems with mobile compartments. BAM, our tool, implements a stochastic version of the BioAmbient calculus and helps in understanding and reasoning about the multiple interconnections between components in bioregulatory networks.