Thiamine deficiency: a commonly unrecognised but easily treatable condition.
Thiamine deficiency: a commonly unrecognised but easily treatable condition.
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DOI：
10.1136/pmj-2022-141972
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发表时间：
2023-08
影响因子：
5.1
通讯作者：
Johnson, Richard Joseph
中科院分区：
文献类型：
--
作者：
Schostak, Tritia;San Millan, Inigo;Jani, Alkesh;Johnson, Richard Joseph
硫胺素存在于许多食物中，被公认为是能量代谢的关键营养素。虽然硫胺素缺乏症通常在酒精中毒中被认识到，但它可以出现在许多其他环境中，在这些环境中，它往往没有被考虑和认识到。诊断的一个挑战性方面是它可能具有不同的代谢，神经和心脏表现。在这里，我们提出了一个概述的障碍，重点是多种原因和临床表现。有趣的是，硫胺素缺乏症的频率可能会增加，特别是在野生动物中，它与不断变化的环境和气候变化有关。无论何时出现病因不明的神经系统或心脏疾病，尤其是出现乳酸酸中毒的患者，都应考虑硫胺素缺乏症。
Thiamine is present in many foods and is well recognised as an essential nutrient critical for energy metabolism. While thiamine deficiency is commonly recognised in alcoholism, it can present in many other settings where it is often not considered and goes unrecognised. One challenging aspect to diagnosis is that it may have varied metabolic, neurological and cardiac presentations. Here we present an overview of the disorder, focusing on the multiple causes and clinical presentations. Interestingly, thiamine deficiency is likely increasing in frequency, especially among wildlife, where it is linked with changing environments and climate change. Thiamine deficiency should be considered whenever neurological or cardiological disease of unknown aetiology presents, especially in any patient presenting with lactic acidosis.
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影响因子：
5
作者：
San-Millan I;Sparagna GC;Chapman HL;Warkins VL;Chatfield KC;Shuff SR;Martinez JL;Brooks GA
通讯作者：
Brooks GA
影响因子：
38.1
作者：
Spinazzi, Marco;Angelini, Corrado;Patrini, Cesare
通讯作者：
Patrini, Cesare
DOI：
10.1073/pnas.79.10.3300
发表时间：
1982-01-01
期刊：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子：
--
作者：
CHUANG, DT;KU, LS;COX, RP
通讯作者：
COX, RP
DOI：
10.1016/s0022-2143(99)90203-2
发表时间：
1999-09-01
期刊：
JOURNAL OF LABORATORY AND CLINICAL MEDICINE
影响因子：
--
作者：
Rieck, J;Halkin, H;Ezra, D
通讯作者：
Ezra, D
重症患者持续静脉血液透析过程中的铜、硒、锌和硫胺素平衡
影响因子：
7.1
作者：
Berger, MM;Shenkin, A;Chioléro, RL
通讯作者：
Chioléro, RL