Influence of pre‐ and intra‐ operative factors on the occurrence of postoperative fatigue
Influence of pre‐ and intra‐ operative factors on the occurrence of postoperative fatigue
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DOI：
10.1002/bjs.1800720124
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发表时间：
1985-01
影响因子：
9.6
通讯作者：
Br. J. Surg;Vol 1985;January 72;T. C. F. Houg6rd;H. Kehlet
中科院分区：
文献类型：
--
作者：
Br. J. Surg;Vol 1985;January 72;T. C. F. Houg6rd;H. Kehlet
52例患者在单纯腹部手术前、术后10、20、30天，15例患者在小耳科手术后进行主观疲劳感觉评估。大手术组疲劳指数从术前的3.0±0.2 （mean±s.e.m）任意单位分别增加到术后第10、20、30天的6.1±0.3、5.3±0.3、4.1±0.3 （P< 0.05）、第20天的2.3±0.4 （P<0.4）、第30天的2.1±0.3 （P<0.9）。两组术后疲劳程度差异有统计学意义（P<0.001），但术前差异无统计学意义（P<0.05）。两组的平均手术时间相似。腹部组术后疲劳的增加与年龄、性别、术前疲劳程度、实际体重、三头肌皮褶厚度（TSF）、臂肌围（AMC）、人体测量指数（体重× TSF × AMC）或血清转铁蛋白无关，但与术前体重与理想体重相关（r = - 0.3， P<0.05）。因此，创伤的大小而不是麻醉的持续时间可能是术后疲劳发生的重要因素。此外，择期腹部手术后的疲劳似乎是无法预测的，从术前状态的病人。
Subjective feeling of fatigue was assessed before and 10, 20 and 30 days after uncomplicated abdominal surgery in 52 patients and after minor otological surgery in 15 patients. In major surgery fatigue increased from 3.0 ± 0.2 (mean±s.e.m.) arbitrary units pre‐operatively to 6.1±0.3, 5.3±0.3 and 4.1±0.3 on day 10, 20 and 30, respectively (P 0.05), day 20 (2.3±0.4) (P<0.4), or day 30 after surgery (2.1±0.3) (P<0.9). Differences in fatigue between groups were significant postoperatively (P<0.001), but not pre‐operatively (P<0.05). Mean duration of surgery was similar in the two groups. In the abdominal group an increase in postoperative fatigue did not correlate with age, sex, pre‐operative degree of fatigue, actual body weight, triceps skinfold thickness (TSF), arm muscle circumference (AMC), anthropometric index (body weight × TSF × AMC) or serum‐transferrin, but did slightly with pre‐operative body weight related to ideal body weight (r = ‐0.3, P<0.05). Thus, the magnitude of the trauma and not the duration of anaesthesia may be important for occurrence of postoperative fatigue. Furthermore, fatigue after elective abdominal surgery seems to be unpredictable from the pre‐operative status of the patient.