Skeletal muscle contractile and noncontractile components in young and older women and men
Skeletal muscle contractile and noncontractile components in young and older women and men
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DOI：
10.1152/jappl.2000.88.2.662
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发表时间：
2000-02-01
影响因子：
3.3
通讯作者：
Young, K
中科院分区：
文献类型：
--
作者：
Kent-Braun, JA;Ng, AV;Young, K
为了研究年龄、性别和习惯性体力活动水平对人体骨骼肌组成的影响，我们开发了一种相对简单的磁共振成像方法，用于定量腿部前室收缩和非收缩含量。我们研究了 23 名年轻人（II 名女性和 12 名男性，26-44 岁）和 21 名老年人（10 名女性和 II 名男性，65-83 岁）健康成年人。 Analysis was by two-factor fags, gender) ANOVA.通过佩戴在腰部 1 周的三维加速计来量化的体力活动在各组之间没有差异。男性比女性具有更大的收缩和非收缩横截面积 (cm(2))，并且性别对非收缩面积百分比没有影响。年轻受试者比老年受试者具有更大的收缩面积和更小的绝对（cm(2)）和相对（总百分比）非收缩面积。老年人的体力活动和非收缩面积百分比之间存在显着的线性关系（r = -0.68，P = 0.002），但年轻受试者则不然。这些数据表明，老年人运动肌的非收缩含量增加了两倍以上，并为身体活动作为这种与年龄相关的肌肉成分变化的调节剂提供了新的支持。
To examine the influences of age, gender, and habitual physical activity level on human skeletal muscle composition, we developed a relatively simple magnetic resonance imaging method for the quantitation of leg anterior compartment contractile and noncontractile content. We studied 23 young (II women and 12 men, 26-44 yr old) and 21 older (10 women and II men, 65-83 yr old) healthy adults. Analysis was by two-factor fags, gender) ANOVA. Physical activity, quantitated by three-dimensional accelerometer worn about the waist for 1 wk, was not different between groups. Men had larger contractile and noncontractile cross-sectional areas (cm(2)) than women, with no gender effect on percent noncontractile area. Young subjects had larger contractile areas and smaller absolute (cm(2)) and relative (percent total) noncontractile areas than older subjects. There was a significant linear relationship between physical activity and percent noncontractile area in older (r = -0.68, P = 0.002) but not young subjects. These data demonstrate a more than twofold increase in the noncontractile content of locomotor muscles in older adults and provide novel support far physical activity as a modulator of this age-related change in muscle composition.