Influence of mastication and edentulism on mandibular bone density
Influence of mastication and edentulism on mandibular bone density
复制标题
DOI：
10.1080/10255842.2013.792916
复制
发表时间：
2015-02-17
影响因子：
1.6
通讯作者：
Mueftue, Sinan
中科院分区：
文献类型：
--
作者：
Chou, Hsuan-Yu;Satpute, Devesh;Mueftue, Sinan
本研究的目的是证明，外部负荷由于日常活动，包括咀嚼，语音和不自觉的开闭周期的颌骨有助于下颌骨的内部结构。骨重建算法，调节骨密度作为应力和加载周期的函数被纳入有限元分析。一个三维计算模型的基础上构建的计算机断层扫描（CT）图像的人下颌骨。咀嚼肌激活过程中所涉及的紧咬建模静态分析，使用线性优化。其他负载条件近似施加下颌弯曲。模拟预测下颌骨密度分布导致管状结构，类似于在CT图像中观察到的。已知这种骨结构提供骨的最佳强度以抵抗咀嚼期间的弯曲和扭转，同时减少骨量。重建算法用于模拟无牙颌对下颌骨骨丢失的影响。研究表明，根据缺失牙齿的位置和数量，由于缺乏足够的机械刺激，可能会损失多达三分之一的下颌骨骨量。
The aim of this study was to demonstrate that external loading due to daily activities, including mastication, speech and involuntary open-close cycles of the jaw contributes to the internal architecture of the mandible. A bone remodelling algorithm that regulates the bone density as a function of stress and loading cycles is incorporated into finite element analysis. A three-dimensional computational model is constructed on the basis of computerised tomography (CT) images of a human mandible. Masticatory muscle activation involved during clenching is modelled by static analysis using linear optimisation. Other loading conditions are approximated by imposing mandibular flexure. The simulations predict that mandibular bone density distribution results in a tubular structure similar to what is observed in the CT images. Such bone architecture is known to provide the bone optimum strength to resist bending and torsion during mastication while reducing the bone mass. The remodelling algorithm is used to simulate the influence of edentulism on mandibular bone loss. It is shown that depending on the location and number of missing teeth, up to one-third of the mandibular bone mass can be lost due to lack of adequate mechanical stimulation.