Six month follow-up of self-reported loss of smell during the COVID-19 pandemic
Six month follow-up of self-reported loss of smell during the COVID-19 pandemic
复制标题
DOI：
10.4193/rhin20.544
复制
发表时间：
2021-01-01
期刊：
影响因子：
7.2
通讯作者：
Kumar, Nirmal
中科院分区：
文献类型：
--
作者：
Hopkins, Claire;Surda, Pavol;Kumar, Nirmal
前言：嗅觉和味觉丧失现在被认为是COVID-19最常见的症状之一，也是COVID-19阳性的最佳预测因素。长期结果未知。这项研究旨在调查嗅觉丧失的恢复情况和嗅觉异常的患病率。方法：对在英国COVID-19大流行开始时自我报告嗅觉丧失的在线手术的受访者进行6个月的随访。额外的症状，恢复嗅觉丧失和嗅觉异常的发展的信息collected.Results：44%的受访者报告至少有一个其他持续的症状，在6个月，其中疲劳（n=106）是最普遍的。嗅觉丧失严重程度的自我评定有显著改善，其中177名患者表示他们有正常的嗅觉，而12名患者报告嗅觉完全丧失。嗅觉异常的患病率为43.1%，平均间隔为2.5个月（范围0-6）从发病的损失smole.Conclusions：虽然许多患者恢复迅速，一些经验的长期赤字没有自我报告的改善，在6个月。此外，嗅觉异常的患病率很高，即使在那些报告至少有一些嗅觉功能恢复的人中。需要对恢复情况进行更长期的评估。
Introduction: Loss of smell and taste is now recognised as amongst the most common symptoms of COVID-19 and the best predictor of COVID-19 positivity. Long term outcomes are unknown. This study aims to investigate recovery of loss of smell and the prevalence of parosmia.Methodology: 6-month follow-up of respondents to an online surgery who self-reported loss of smell at the onset of the COVID-19 pandemic in the UK. Information of additional symptoms, recovery of loss of smell and the development of parosmia was collected.Results: 44% of respondents reported at least one other ongoing symptom at 6 months, of which fatigue (n=106) was the most prevalent. There was a significant improvement in self-rating of severity of olfactory loss where 177 patients stated they had a normal smell of smell while 12 patients reported complete loss of smell. The prevalence of parosmia is 43.1% with median interval of 2.5 months (range 0-6) from the onset of loss of smell.Conclusions: While many patients recover quickly, some experience long-term deficits with no self-reported improvement at 6 months. Furthermore, there is a high prevalence of parosmia even in those who report at least some recovery of olfactory function. Longer term evaluation of recovery is required.