Fast-spreading SARS-CoV-2 variants: challenges to and new design strategies of COVID-19 vaccines.

Fast-spreading SARS-CoV-2 variants: challenges to and new design strategies of COVID-19 vaccines.
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DOI:
10.1038/s41392-021-00644-x
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发表时间:
2021-06-09
影响因子:
39.3
通讯作者:
Wang W
Wang W
中科院分区:
医学1区
文献类型:
--
作者:
Zhou W;Wang W

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由严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 引起的 COVID-19 大流行仍然威胁着全球健康。最新数据显示,确诊病例已突破1亿。令人欣慰的是,通过对该疾病的病毒学、免疫学、流行病学和临床研究,在预防和治疗COVID-19方面已经积累了经验。 1此外,不同疫苗的不断进步带来了战胜疫情的曙光。 2 然而,2020 年底报道了快速传播的 SARS-CoV-2 突变株(B. 1.1. 7、B. 1.351 和 B. 1.1. 28.1)的出现,引起了人们对 COVID-19 预防和治疗的担忧。据推测,SARS-CoV-2变种的出现可能预示着大流行进入一个新阶段。 3
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still threatening global health. According to the latest data, the number of diagnosed cases has exceeded 100 million. Comfortingly, experiences have been accumulated in preventing and treating COVID-19 through virological, immunological, epidemiological, and clinical investigations of this disease. 1 Besides, the continuous advancement of different vaccines brings the dawn to defeat the epidemic. 2 However, the emergence of fast-spreading SARS-CoV-2 mutant strains (B. 1.1. 7, B. 1.351, and B. 1.1. 28.1) was reported at the end of 2020, causing concern to prevention and treatment of COVID-19. It is speculated that the emergence of the SARS-CoV-2 variants may portend a new phase of the pandemic. 3
SARS-COV-2血统的估计可传播和影响B.1.1.7在英国。
DOI: 10.1126/science.abg3055
发表时间: 2021-04-09
期刊: Science (New York, N.Y.)
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DOI: 10.1101/2021.02.01.21250959
发表时间: 2021-03-15
期刊: NATURE
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