The role of bacterial infections in asthma
The role of bacterial infections in asthma
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DOI：
10.1016/s0272-5231(05)70268-9
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发表时间：
2000-06-01
影响因子：
5.7
通讯作者：
Kraft, M
中科院分区：
文献类型：
--
作者：
Kraft, M
细菌是众所周知的哮喘恶化的致病生物体，并给患者及其临床医生带来重大问题。细菌有机体可以增加已知哮喘患者的气道高反应性和炎症，但现在的问题是这些相同的机制是否可能导致哮喘的发展。这篇文章提供了证据表明，特定的微生物，肺炎支原体和肺炎衣原体，是已知的加剧哮喘，但可能参与哮喘的发病机制。
Bacteria are well known causative organisms in the exacerbation of asthma and pose significant problems for patients and their clinicians. Bacterial organisms can increase airway hyper-responsiveness and inflammation in the patient with known asthma, but now the question arises whether these same mechanisms may be responsible for the development of asthma. This article presents evidence that specific organisms, Mycoplasma pneumoniae and Chlamydia pneumoniae, are known to exacerbate asthma, but may be involved in asthma pathogenesis.