Excretion in mammals: role of the renal pelvis in the modification of the urinary concentration and composition.
Excretion in mammals: role of the renal pelvis in the modification of the urinary concentration and composition.
复制标题
哺乳动物的排泄：肾盂在改变尿液浓度和成分中的作用。
DOI：
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发表时间：
1977
期刊：
影响因子：
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通讯作者：
B. Schmidt
中科院分区：
文献类型：
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作者：
B. Schmidt
哺乳动物的肾盂以前被认为除了在尿液通过输尿管之前作为尿液的容器之外没有任何生理功能。人们早就知道，哺乳动物的肾盂表现出复杂的延伸，使尿液与外部和内部髓质组织密切接触。覆盖这些区域的上皮细胞类型表明溶质和水可以穿过其运输。生理学研究表明，尿素和水很容易穿过肾乳头状上皮。反刍动物在低蛋白饮食时保存尿素的显着能力与高度发达的肾盂、专门的穹窿和次级囊袋相一致。有人认为，低蛋白动物的尿素保存部分发生在尿素返回血液的肾盂延伸部分。还提出了一种关于浓缩机制的假设，其中尿素从盆腔尿液穿过乳头状上皮的再循环发挥着重要作用。
The mammalian renal pelvis has previously been regarded as having no physiological function other than that of a receptacle for the urine before it moves through the ureter. It has long been known that the renal pelvis in mammals shows elaborate extensions that bring the urine in intimate contact with outer and inner medullary tissue. The epithelium covering these areas is of a type that indicates that transport of solutes and water can take place across it. Physiological studies have shown that urea and water readily move across the renal papillary epithelium. The pronounced ability of ruminants to conserve urea when placed on a low protein diet coincides with a highly developed renal pelvis with specialized fornices and secondary pouches. It is suggested that urea conservation in low protein animals takes place partly in the renal pelvic extensions where urea is returned to the blood. A hypothesis is also proposed for the concentrating mechanism in which recycling of urea from the pelvic urine across the papillary epithelium plays an important role.