SLEEP AND CIRCADIAN RHYTHM DISORDERS IN PARKINSON'S DISEASE.
SLEEP AND CIRCADIAN RHYTHM DISORDERS IN PARKINSON'S DISEASE.
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DOI：
10.1007/s40675-017-0079-y
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发表时间：
2017-09
影响因子：
1.8
通讯作者：
Videnovic A
中科院分区：
文献类型：
--
作者：
Gros P;Videnovic A
睡眠障碍是帕金森病（PD）最具挑战性的非运动特征之一，并显着影响生活质量。这一领域的研究最近引起了临床医生和科学家的兴趣，并正在迅速发展。这篇综述致力于与PD相关的睡眠和昼夜节律功能障碍。大多数原发性睡眠障碍可能与PD共存;大多数这些疾病在PD人群中表达时具有独特的特征。我们讨论了帕金森病常见的睡眠问题，包括失眠，快速眼动睡眠行为障碍，不宁腿综合征，睡眠呼吸障碍，白天过度嗜睡和昼夜节律紊乱的具体考虑。在这些睡眠障碍，我们目前更新的定义，流行病学，病因，诊断，临床意义和管理。此外，还概述了进一步研究的潜在兴趣领域。
Sleep disorders are among the most challenging non-motor features of Parkinson’s disease (PD) and significantly affect quality of life. Research in this field has gained recent interest among clinicians and scientists and is rapidly evolving. This review is dedicated to sleep and circadian dysfunction associated with PD. Most primary sleep disorders may co-exist with PD; majority of these disorders have unique features when expressed in the PD population. We discuss the specific considerations related to the common sleep problems in Parkinson’s disease including insomnia, rapid eye movement sleep behavior disorder, restless legs syndrome, sleep disordered breathing, excessive daytime sleepiness and circadian rhythm disorders. Within each of these sleep disorders, we present updated definitions, epidemiology, etiology, diagnosis, clinical implications and management. Furthermore, areas of potential interest for further research are outlined.