Emotion-related cerebral blood flow changes in the ventral medial prefrontal cortex: An NIRS study
Emotion-related cerebral blood flow changes in the ventral medial prefrontal cortex: An NIRS study
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DOI：
10.1016/j.bandc.2019.05.001
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发表时间：
2019-08-01
影响因子：
2.5
通讯作者：
Hiraki, Kazuo
中科院分区：
文献类型：
--
作者：
Ozawa, Sachiyo;Kanayama, Noriaki;Hiraki, Kazuo
本研究探讨了前腹内侧前额叶皮层（VMPFC）的脑血流量（CBF）变化是否代表对情绪刺激的反应，而不是我们以前的近红外光谱（NIRS）研究所建议的分心任务期间的情绪认知控制。MPFC区域的功能区分有时很困难，因为它们具有多种功能。在这里，我们解决了一些剩余的问题，从我们以前的分心研究，并采用分心范式，其中负面或中性的图像作为情绪刺激，休息时间包括在一个条件和工作记忆（分心）任务在其他。为了提取与消极情绪刺激反应相关的CBF变化（定义为情绪相关的CBF变化），我们从消极条件下获得的CBF变化中减去中性条件下获得的CBF变化。我们发现，情绪相关的CBF的变化，在左前VMPFC在休息条件下显着大于在分心任务条件。这些结果表明，分心任务减少了不必要的大脑活动，从而减少了情绪相关的CBF变化。他们支持我们以前的研究结果，表明CBF的变化，在前VMPFC地区，使用近红外光谱测量，具体与情绪刺激的反应。
The current study examined whether cerebral blood flow (CBF) changes in the anterior ventral medial prefrontal cortex (VMPFC) represent responses to emotional stimuli instead of cognitive control of emotion during distraction tasks, as suggested by our previous near-infrared spectroscopy (NIRS) study. The functional distinction of MPFC regions is occasionally difficult due to their multiple functions. Here, we addressed some remaining concerns from our previous distraction studies, and employed the distraction paradigm, in which negative or neutral images are presented as emotional stimuli; a rest period is included in one condition and working memory (distraction) tasks in the other. To extract the components of CBF changes associated with responses to negative emotional stimuli (defined as emotion-related CBF changes), we subtracted the CBF changes obtained in the neutral condition from those in the negative condition. We found that emotion-related CBF changes in the anterior left VMPFC were significantly greater in the rest condition than in the distraction task condition. These findings imply that the distraction task decreased unnecessary brain activities, resulting in decrease in the emotion-related CBF changes. They support our previous findings, indicating that CBF changes in anterior VMPFC regions, measured using NIRS, are specifically associated with responses to emotional stimuli.