Locomotor training after human spinal cord injury: A series of case studies
Locomotor training after human spinal cord injury: A series of case studies
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DOI：
10.1093/ptj/80.7.688
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发表时间：
2000-07-01
期刊：
影响因子：
3.2
通讯作者：
Harkema, SJ
中科院分区：
文献类型：
--
作者：
Behmran, AL;Harkema, SJ
许多脊髓损伤（SCI）患者无法恢复行走能力，尽管这是康复的主要目标。胸脊髓横断的哺乳动物可以在跑步机上重新学习用后肢行走，训练时与行走相关的感觉输入。如果人类有类似的运动神经机制，那么提供类似的训练可能会促进SCI后的运动恢复。我们使用运动训练来提供与运动相关的感觉信息，以改善SCI后成人的步行和行走。4名SCI患者平均伤后6个月接受运动训练。根据美国脊髓损伤协会（ASW）损伤量表和神经系统分类标准，受试者1的T5损伤分类为ASIA A，受试者2的T5损伤分类为ASLA C，受试者3的C6损伤分类为ASLA D，受试者4的T9损伤分类为ASIA D。所有受试者都改善了他们在跑步机上的踏步。1例受试者实现了地上行走，2例受试者改善了地上行走。利用人体脊髓对与运动相关的传感器信息的反应进行运动训练可能会改善SCI后行走的潜在恢复。
Many individuals with spinal cord injury (SCI) do not regain their ability to walk, even though it is a primary goal of rehabilitation. Mammals with thoracic spinal cord transection can relearn to step with their hind limbs on a treadmill when trained with sensory input associated with stepping. If humans have similar neural mechanisms for locomotion, then providing comparable training may promote locomotor recovery after SCI. We used locomotor training designed to provide sensory information associated with locomotion to improve stepping and walking in adults after SCI. Four adults with SCIs, with a mean postinjury time of 6 months, received locomotor training. Based on the American Spinal Injury Association (ASW) Impairment Scale and neurological classification standards, subject 1 had a T5 injury classified as ASIA A, subject 2 had a T5 injury classified as ASLA C, subject 3 had a C6 injury classified as ASLA D, and subject 4 had a T9 injury classified as ASIA D. All subjects improved their stepping on a treadmill. One subject achieved overground walking, and 2 subjects improved their overground walking. Locomotor training using the response of the human spinal cord to sensor information related to locomotion may improve the potential recovery of walking after SCI.