MR coronary angiography in pigs with intraarterial injections of a hyperpolarized 13C substance
MR coronary angiography in pigs with intraarterial injections of a hyperpolarized 13C substance
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动脉内注射超极化 13C 物质对猪进行 MR 冠状动脉造影
DOI：
10.1002/mrm.20847
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发表时间：
2006
影响因子：
3.3
通讯作者：
J. Petersson
中科院分区：
文献类型：
--
作者：
L. Olsson;C. Chai;O. Axelsson;M. Karlsson;K. Golman;J. Petersson
介绍了一种基于13C物质超极化的水溶性造影剂(CM)的新诊断应用。获得的偏振度为>；30%，比1.5T时的热平衡极化水平高约105倍。研究了心脏介入性核磁共振检查中超极化CM的成像。将导管放置在猪的左、右冠状动脉内。使用调谐到13C的线圈进行非质子成像。HP-13C CM(∼5ml，0.5M，∼30%极化)在投影成像过程中使用完全平衡的稳态自由进动脉冲序列进行注射，其中有无心脏门控。在手术过程中，充填造影剂的导管清晰可见。冠状动脉显示良好，信噪比(SNR)在10~40之间。HP-13C CM的应用可能为介入性MRI提供一种新的诊断方法。Magn Reson Med，2006。©2006 Wiley-Liss，Inc.
A new diagnostic application of a water‐soluble contrast medium (CM) based on the hyperpolarization of a 13C substance is introduced. The degree of polarization achieved is >30%, which is about a factor of 105 higher than the thermal equilibrium polarization level at 1.5 T. Imaging of hyperpolarized (HP) CM during a cardiac interventional MRI procedure was studied. Catheters were positioned in the left and right coronary arteries of pigs. A coil tuned to 13C was used for nonproton imaging. The HP‐13C CM (∼5 ml, 0.5 M, ∼30% polarization) was injected during projection imaging using a fully balanced steady‐state free precession (SSFP) pulse sequence with and without cardiac gating. The contrast agent‐filled catheter was clearly visible during the procedure. The coronary arteries were well depicted and the signal‐to‐noise ratios (SNRs) were in the range of 10–40. The use of HP‐13C CM may provide a new diagnostic procedure for interventional MRI. Magn Reson Med, 2006. © 2006 Wiley‐Liss, Inc.
实时投影磁共振血管造影：可行性研究。
DOI：
10.1148/radiology.217.1.r00se42290
发表时间：
2000
期刊：
Radiology.
影响因子：
--
作者：
Serfaty,JM;Atalar,E;Declerck,J;Karmakar,P;Quick,HH;Shunk,KA;Heldman,AW;Yang,X
通讯作者：
Yang,X
影响因子：
19.7
作者：
MacFall, JR;Charles, HC;Ravin, CE
通讯作者：
Ravin, CE