Quantitative 3D soft tissue analysis of symmetry prior to and after unilateral cleft lip repair compared with non-cleft persons (performed in Cambodia)
Quantitative 3D soft tissue analysis of symmetry prior to and after unilateral cleft lip repair compared with non-cleft persons (performed in Cambodia)
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DOI：
10.1016/j.jcms.2008.05.003
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发表时间：
2008-12-01
影响因子：
3.1
通讯作者：
Zeilhofer, Hans-Florian
中科院分区：
文献类型：
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作者：
Schwenzer-Zimmerer, Katja;Chaitidis, Despina;Zeilhofer, Hans-Florian
对象：本研究的目的是评估三维（3D）成像和形态学分析的临床应用，随后的个人治疗计划和术后3D对称性控制与非唇腭裂患者的数据进行比较。设计：这是一项使用3D表面成像和评估系统对唇裂患者和非唇裂患者进行的前瞻性研究。使用3D激光扫描仪记录患者术前和术后的3D面部轮廓。对术前三维图像进行定性和定量分析，以制定个体化治疗计划。在比率和分数的基础上，基于经验感兴趣区域，单独设计裂隙修复技术。评价术后结果的对称性。手术产生的软组织移位定量定义，并与矢量可视化。术后的对称性进行了比较，从一组非唇腭裂的人相同的种族组的三维数据。患者：11例单侧孤立性唇裂、唇裂和齿槽裂或单侧完全性唇裂、齿槽裂和腭裂患者（平均年龄13.8岁，中位数13岁，最小年龄2岁，最大年龄41岁）和25例非唇裂患者（8例4 - 12岁儿童，17例18 - 50岁成人（9例男性，8例女性））。所有这些被调查的人都是高棉裔的亚洲人。结果：分析允许定量的3D评价。收集了无唇腭裂高棉人的三维人体测量数据，并将其命名为该民族对称性的黄金标准。所有术后3D图像均达到正常队列范围内的对称值。从术前到术后部位的软组织移位可见。结论：描述了一种新的配准方法，可在患者年龄增长时进行随访配准。这种三维软组织分析可以是一个有用的工具，在定量分析和客观的后续控制在腭裂患者。它提供了更深入的了解要治疗的复杂形态，并可能有助于个性化的外科手术。(C)2008年欧洲颅颌面外科协会
Object: The aim of this study was to evaluate the clinical application of three-dimensional (3D) imaging and morphological analysis with subsequent individual therapy planning and postoperative 3D symmetry control in comparison with data from non-cleft persons. Design: This was a prospective study using a 3D surface-imaging and evaluation system in cleft patients and non-cleft persons. The pre- and postoperative 3D facial profiles were recorded from the patients using a 3D laser scanner. The preoperative 3D image was analyzed qualitatively and quantitatively for an individual therapy planning. On the basis of ratios and scores, based on empirical regions of interest, the technique of cleft repair was designed individually. The postoperative result was evaluated regarding symmetry. The surgically created soft tissue shift was defined quantitatively and visualized with vectors. The postoperative symmetry was compared with 3D data from a group of non-cleft persons of the same ethnical group. Patients: Eleven patients (mean age 13.8 years, median 13, minimum 2, maximum 41 years) with either a unilateral isolated cleft lip, a cleft lip and alveolus or a complete unilateral cleft lip, alveolus and palate and 25 non-cleft persons (8 children between 4 and 12 years, 17 adults (9 men, 8 women) between 18 and 50 years). All these persons investigated were Asians of Khmer origin. Results: The analysis permitted quantitative 3D evaluation. The 3D anthropometric data of the non-cleft Khmer persons were collected and named the gold standard of symmetry in this ethnical group. All postoperative 3D images reached symmetrical values within the range of the normal cohort. Soft tissue shifts from pre- to postoperative sites could be visualized. Conclusion: A new method for registration was described enabling follow-up registration in patients when growing older. This 3D soft tissue analysis can be a useful tool in quantitative analysis and objective follow-up control in cleft patients. It offers deeper insight into the complex morphology to be treated and could contribute to individualisation of surgical procedures. (C) 2008 European Association for Cranio-Maxillofacial Surgery