Rapid and coordinated processing of global motion images by local clusters of retinal ganglion cells.
Rapid and coordinated processing of global motion images by local clusters of retinal ganglion cells.
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DOI：
10.2183/pjab.93.015
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Tachibana M
中科院分区：
文献类型：
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作者：
Matsumoto A;Tachibana M
即使当身体静止时，整个视网膜图像也总是通过在固定点之间移动眼睛的固定眼球运动和扫视而运动。越来越多的证据表明，大脑具有特定的机制来补偿这些眼球运动引起的全局运动。然而，还没有完全理解视网膜如何在眼睛运动期间处理全局运动图像。在这里，我们表明，全球运动图像引起视网膜神经节细胞（GC）的新的协调放电。我们同时记录了发射的GC在金鱼离体视网膜使用多电极阵列，并分类每个GC的基础上，其感受野（RF）的时间分布。一个移动的目标，伴随着全球的运动（模拟一段时间的注视眼球运动后的扫视）调制的RF特性和诱发同步和相关的特定GC的局部集群之间的发射。我们的研究结果提供了一个新的概念，视网膜信息处理过程中的眼球运动。
Even when the body is stationary, the whole retinal image is always in motion by fixational eye movements and saccades that move the eye between fixation points. Accumulating evidence indicates that the brain is equipped with specific mechanisms for compensating for the global motion induced by these eye movements. However, it is not yet fully understood how the retina processes global motion images during eye movements. Here we show that global motion images evoke novel coordinated firing in retinal ganglion cells (GCs). We simultaneously recorded the firing of GCs in the goldfish isolated retina using a multi-electrode array, and classified each GC based on the temporal profile of its receptive field (RF). A moving target that accompanied the global motion (simulating a saccade following a period of fixational eye movements) modulated the RF properties and evoked synchronized and correlated firing among local clusters of the specific GCs. Our findings provide a novel concept for retinal information processing during eye movements.