A right handed peptide helix containing a central double D-amino acid segment

A right handed peptide helix containing a central double D-amino acid segment
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DOI:
10.1039/b207960g
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发表时间:
2002-01-01
影响因子:
4.9
通讯作者:
Balaram, P
Balaram, P
中科院分区:
化学2区
文献类型:
--
作者:
Aravinda, S;Shamala, N;Balaram, P

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13个残基肽Boc-Leu-Aib-Val-Ala-Leu-Aib-Val-(D)Ala-(D) leu - aib - Leu-Aib-Leu-Aib-Val-OMe的晶体结构揭示了一个连续的螺旋构象,提供了右手肽螺旋中连续D残基的明确表征。
The crystal structure of the 13 residue peptide Boc-Leu-Aib-Val-Ala-Leu-Aib-Val-(D)Ala-(D)Leu-Aib-Leu-Aib-Val-OMe reveals a continuous helical conformation providing an unambiguous characterization of contiguous D-residues in a right handed peptide helix.