Cu2+ assisted carnation-like fluorescent metal–organic framework for triple-mode detection of glyphosate in food samples
Cu2+ assisted carnation-like fluorescent metal–organic framework for triple-mode detection of glyphosate in food samples
复制标题
Cu2辅助康乃馨类荧光金属有机框架用于食品样品中草甘膦的三重模式检测
DOI：
10.1016/j.foodchem.2022.135237
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发表时间：
2022
期刊：
影响因子：
8.8
通讯作者：
Xiaoqing Chen
中科院分区：
文献类型：
--
作者：
Jianping Guan;Qing He;Qi Liu;Xiaoqing Chen
本文采用新型配体H2 L构建了一个具有花状发光结构的金属有机骨架IRMOF-3-L，并将其用于构建检测草甘膦（Glyp）的三模式传感器。配体H2 L被设计成包含三个功能部分，这赋予了IRMOF-3-L类似过氧化物酶的活性和独特的荧光性质，以及对Cu ~（2+）的特异结合能力，使其荧光猝灭。IRMOF-3-L/Cu ~（2+）体系的荧光猝灭后，Glyp可恢复其荧光，实现Glyp的荧光检测。此外，Glyp还能抑制IRMOF-3-L/Cu ~（2+）的过氧化物酶活性，导致oxTMB催化量减少，同时也降低了色度和Sers信号的变化。因此，基于荧光/比色/Sers三重模式的Glyp检测被有利地实现，并且计算的检测限分别低至0.738、2.26和0.186 nM。此外，构建了便携式测试条-智能手机传感平台，用于食品样品中Glyp的即时检测。
Herein, by employing a novel synthesized ligand H2L, a flower-like luminescent metal–organic frameworkIRMOF-3-Lwas constructed for developing a triple-mode sensor for glyphosate (Glyp) detection. The ligand H2L was designed to contain three functional parts, which endowed the resultedIRMOF-3-Lwith peroxidase-like activity and unique fluorescence property, as well as specific combining capacity for Cu2+to quench its fluorescence. The quenched fluorescence ofIRMOF-3-L/Cu2+could be recovered by Glyp to realize fluorescence detection of Glyp. Besides, the peroxidase activity ofIRMOF-3-L/Cu2+could also be inhibited by Glyp, and result in the decrease of catalysate oxTMB, concurrently reducing the changes of colorimetric and SERS signal. Therefore, the fluorescent/colorimetric/SERS triple-mode based detection of Glyp was favorably realized, and the detection limits were calculated as low as 0.738, 2.26 and 0.186 nM, respectively. Furthermore, a portable test strips-smartphone sensing platform was constructed for point of care testing of Glyp in food samples.