Projection neurons originating from thermo- and hygrosensory glomeruli in the antennal lobe of the cockroach
Projection neurons originating from thermo- and hygrosensory glomeruli in the antennal lobe of the cockroach
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DOI：
10.1002/cne.10450
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发表时间：
2003-01-01
影响因子：
2.5
通讯作者：
Mizunami, M
中科院分区：
文献类型：
--
作者：
Nishino, H;Yamashita, S;Mizunami, M
大多数昆虫都配备了专门的温度和湿度感受器，以分别确定环境温度和远距离水源的允许范围。在美洲大蠊（Periplaneta americana）中，触角中的冷、湿和干燥的受体细胞将轴突发送到触角叶（初级嗅觉中心）背中央部分的特定两组或三组肾小球，称为DC 1 -3肾小球。然而，目前还不知道如何从这些肾小球的温度和湿度传感器信号表示在更高级别的中心，大脑，在任何昆虫物种。随着细胞内记录和染色技术的使用，我们确定了一类新的中间神经元与树突几乎完全在DC 1，DC 2，或DC 3肾小球和轴突投射到蟑螂的前脑。值得注意的是，所有这些投射神经元（PN）的终端覆盖几乎相同的区域在外侧前脑（LP），虽然他们的终止区以外的LP不同的神经元。终止领域内的LP是不同的，但接近，那些uniglomerular和macroglomerular PN的传输信号，一般气味和女性性信息素，分别。起源于DC 1，DC 2和DC 3肾小球的PN表现出兴奋性反应冷，潮湿，干燥的刺激，分别可能是由于兴奋性突触输入冷，潮湿，干燥的受体细胞，而它们的反应往往调制的嗅觉刺激。这些结果表明，背中央PNs参与神经通路，导致行为反应的温度或湿度的变化。(C)2002 Wiley-Liss，Inc.
Most insects are equipped with specialized thermo- and hygroreceptors to locate a permissible range of ambient temperature and distant water sources, respectively. In the cockroach, Periplaneta americana, cold, moist, and dry receptor cells in the antennae send axons to particular sets of two or three glomeruli in the dorsocentral part of the antennal lobe (primary olfactory center), designated DC1-3 glomeruli. However, it is not known how thermo- and hygrosensory signals from these glomeruli are represented in higher-order centers, the protocerebrum, in any insect species. With the use of intracellular recording and staining techniques, we identified a new class of interneurons with dendrites almost exclusively in the DC1, DC2, or DC3 glomeruli and axons projecting to the protocerebrum in the cockroach. Remarkably, terminals of all these projection neurons (PNs) covered almost identical areas in the lateral protocerebrum (LP), although their termination areas outside the LP differed from neuron to neuron. The termination areas within the LP were distinct from, but close to, those of uniglomerular and macroglomerular PNs that transmitted signals concerning general odors and female sex pheromones, respectively. PNs originating from DC1, DC2, and DC3 glomeruli exhibited excitatory responses to cold, moist, and dry stimuli, respectively, probably due to excitatory synaptic input from cold, moist, and dry receptor cells, respectively, whereas their responses were often modulated by olfactory stimuli. These findings suggested that dorsocentral PNs participate in neural pathways that lead to behavioral responses to temperature or humidity changes. (C) 2002 Wiley-Liss, Inc.