Strategies Exploited by Influenza A Virus for Evading Immune Responses
Strategies Exploited by Influenza A Virus for Evading Immune Responses
复制标题
甲型流感病毒利用的逃避免疫反应的策略
DOI：
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发表时间：
2008
期刊：
影响因子：
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通讯作者：
Zheng Yu-Shu
中科院分区：
文献类型：
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作者：
Zhao Pu;Jia Bei-Bei;Liu Xing-You;Qiao Chuan-Ling;Zheng Yu-Shu
Influenza A virus(IAV) infection is a major cause of respiratory disease in human and many kinds of animals, however, either seasonal"flu" outbreaks or periodic world-wide pandemics caused by IAV is mainly attributed to strategies exploited by IAV for evading antiviral immune responses of the host. There is growing evidence that IAV has evolved highly sophisticated strategies to overcome the antiviral signaling, such as antigen variation and encoding accessory proteins(NS1 and PB1-F2). A better understanding of the strategies exploited by viruses for evading the immunity is helpful for us to reveal the pathogenesis of IAV infection and discover targets for the development of antiviral reagents directed against IAV. Therefore,the latest progress on strategies exploited by IAV for evading antiviral immunity are reviewed.
