Joint approaches to reduce cadmium exposure risk from rice consumption
Joint approaches to reduce cadmium exposure risk from rice consumption
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DOI：
10.1016/j.jhazmat.2022.128263
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发表时间：
2022-01-22
影响因子：
13.6
通讯作者：
Zhuang, Ping
中科院分区：
文献类型：
--
作者：
Mao, Peng;Wu, Jingtao;Zhuang, Ping
原位土壤镉（Cd）固定有助于减少Cd在水稻籽粒中的积累，但其对水稻消化过程中Cd生物可利用性的影响以及与之相关的健康风险尚不清楚。在这里，我们结合原位土壤镉固定和生物可及性校正的健康风险评估（HRA），以尽量减少风险和不确定性的镉暴露从大米消费。在稻田土壤上施用硅灰石和4种不同的磷酸盐（P），研究其对土壤Cd、稻米必需元素和氨基酸的影响。此外，生物可及性校正的HRA进行，以准确地反映镉暴露的风险，从摄入这些水稻。结果表明，硅灰石与4种不同磷配施对水稻籽粒中Cd含量的降低效果相同，但对水稻Cd生物可利用性的影响不一致（53-71%）。基于水稻中Cd生物可利用性的HRA结果表明，施用硅灰石的水稻Cd暴露风险最低，其次是硅灰石和六偏磷酸钠的联合施用。这项工作突出了生物可及性校正HRA筛选最佳镉固定策略，以实现更安全的大米消费的价值。
In-situ soil cadmium (Cd) immobilization helps to reduce Cd accumulation in rice grain, while its effects on bioaccessibility of Cd in rice during digestion and the associated health risk from rice consumption remain unclear. Here, we combined in-situ soil Cd immobilization and bioaccessibility-corrected health risk assessment (HRA) to minimize both the risk and uncertainty of Cd exposure from rice consumption. Wollastonite with or without four different phosphates (P) were applied to immobilize soil Cd at paddy fields, and their influences on Cd, essential elements, and amino acids in rice grain were analyzed. Moreover, a bioaccessibility-corrected HRA was conducted to accurately reflect the Cd exposure risk from ingesting these rices. The results showed the co-application of wollastonite and four different P reduced Cd concentrations in rice grain equally, while their impacts on bioaccessibility of Cd in rice during simulated human digestion were inconsistent (53-71%). The HRA based on bioaccessibility of Cd in rice revealed that Cd exposure risk from rice consumption was lowest with the application of wollastonite, followed by the co-application of wollastonite and sodium hexametaphosphate. This work highlights the value of bioaccessibility-corrected HRA for screening the optimal Cd immobilization strategy to achieve safer rice consumption.