Overview of revised measures to prevent malaria transmission by blood transfusion in France

Overview of revised measures to prevent malaria transmission by blood transfusion in France
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DOI:
10.1111/j.1423-0410.2008.01090.x
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发表时间:
2008-10-01
期刊:
影响因子:
2.7
通讯作者:
de Micco, P.
de Micco, P.
中科院分区:
医学4区
文献类型:
--
作者:
Garraud, O.;Assal, A.;de Micco, P.

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在非疟疾流行国家,通过献血传播疟原虫的情况很少见,但这是一种非常严重的输血并发症。法国国家血液服务机构(法国国家血站和Armees输血中心)打算修订加强血液安全的措施,将疟原虫视为可传播的病原体。为了限制输液过程中的传播风险,法国十多年来一直采取认真的添加措施,法国是感染输入性疟原虫感染或疟疾风险最高的欧洲国家。在2002年发生致命的输血传播感染后,这些措施得到了修订和加强,但没有防止2006年再次发生这种情况。本报告审查了这些系统的弱点,旨在强调已经采取的安全措施,并探讨如何最好地应对这一风险的问题。
Plasmodial transmission by blood donation is rare in non-endemic countries, but a very serious complication of blood transfusion. The French national blood service (Etablissement Francais du Sang and Centre de Transfusion sanguine des Armees) intended to revise the measures to strengthen blood safety with regard to Plasmodiae as transmissible pathogens. To limit the risk of transmission during infusion, serious additive measures have been taken for more than a decade in France, which is the European country with the highest rate of exposure to imported plasmodial infections or malaria. These measures were revised and strengthened after the occurrence of a lethal transfusion-transmitted infection in 2002, but did not prevent another occurrence in 2006. This report examines the weaknesses of the systems and aims at emphasizing the safety measures already taken and addresses issues to best respond to that risk.