Predicting Pregnancy in HIV-1-Discordant Couples
Predicting Pregnancy in HIV-1-Discordant Couples
复制标题
DOI：
10.1007/s10461-010-9716-x
复制
发表时间：
2010-10-01
影响因子：
4.4
通讯作者：
Farquhar, Carey
中科院分区：
文献类型：
--
作者：
Guthrie, Brandon L.;Choi, Robert Y.;Farquhar, Carey
本研究探讨了肯尼亚内罗毕HIV-1不一致夫妇怀孕的发生率和预测因素。研究人员对454对不和谐夫妇的女性进行了长达2年的随访。一年累积妊娠发生率为9.7%。HIV-1感染者和未感染者的妊娠率无显著差异（HR = 1.46）。大多数怀孕发生在30岁以下的妇女中，报告说她们希望将来有孩子（1年发生率为22.2%）。不和谐夫妇的怀孕率可能很高，这表明对孩子的渴望可能会压倒对HIV-1传播的担忧，并增加无保护的性行为，并强调有必要使怀孕更安全。
This study examines the incidence and predictors of pregnancy in HIV-1-discordant couples from Nairobi, Kenya. Women from 454 discordant couples were followed for up to 2 years. One-year cumulative incidence of pregnancy was 9.7%. Pregnancy rates did not differ significantly between HIV-1-infected and uninfected women (HR = 1.46). The majority of pregnancies occurred among women < 30 years old reporting a desire for future children (1-year incidence 22.2%). Pregnancy rates may be high among discordant couples, indicating desire for children may override concerns of HIV-1 transmission and increase unprotected sex, and highlighting the need to make conception safer.