Gastrointestinal Symptoms Predict the Outcomes From COVID-19 Infection.
Gastrointestinal Symptoms Predict the Outcomes From COVID-19 Infection.
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胃肠道症状预测了Covid-19感染的结果。
DOI：
10.1097/mcg.0000000000001513
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发表时间：
2022-02-01
影响因子：
2.9
通讯作者：
Mahdavinia M
中科院分区：
文献类型：
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作者：
Bishehsari F;Adnan D;Deshmukh A;Khan SR;Rempert T;Dhana K;Mahdavinia M
2019冠状病毒病（COVID-19）已夺去全球数十万人的生命。除呼吸道外，该病毒还可感染胃肠道。关于胃肠道症状在COVID-19病程中的重要性的数据有限。在这项迄今为止美国规模最大的研究中，我们回顾了2020年3月12日至4月3日期间连续1003名病毒检测呈阳性的患者的电子接触。高达22.4%的患者出现初始胃肠道症状，并且在调整人口统计学、合并症和其他临床症状后，与较差的结果相关。累及胃肠道的COVID-19可能定义更严重的表型。
Coronavirus disease 2019 (COVID-19) has taken hundreds of thousands of lives globally. Besides respiratory tract, the virus can affect the gastrointestinal (GI) tract. Data regarding the significance of GI symptoms in the COVID-19 course is limited. In this largest U.S. study to-date, we reviewed electronic encounters of 1003 consecutive patients who were tested positive for the virus between March 12th and April 3rd, 2020. Initial GI symptoms were present in up to 22.4% of patients and were associated with worse outcomes after adjustment for demographics, comorbidities and other clinical symptoms. COVID-19 with GI involvement may define a more severe phenotype.