Sagittal spino-pelvic alignment in adults: The Wakayama Spine Study.
Sagittal spino-pelvic alignment in adults: The Wakayama Spine Study.
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DOI：
10.1371/journal.pone.0178697
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发表时间：
2017
期刊：
影响因子：
3.7
通讯作者：
Yoshida M
中科院分区：
文献类型：
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作者：
Asai Y;Tsutsui S;Oka H;Yoshimura N;Hashizume H;Yamada H;Akune T;Muraki S;Matsudaira K;Kawaguchi H;Nakamura K;Tanaka S;Yoshida M
利用基于社区的大型队列建立脊柱-骨盆排列的正常值并阐明与年龄相关的变化的影响。在这项研究中，分析了 1461 名参与者（466 名男性，995 名女性）的数据。在侧位站立X光片上，测量以下参数：胸椎后凸（TK）、腰椎前凸（LL）、骨盆倾斜（PT）、骨盆倾角（PI）和C7矢状垂直轴（SVA）。所有值均表示为平均值±标准差。 Spearman 等级相关系数用于检查脊柱骨盆参数变量之间的相关性。最后，我们分析了年龄与脊柱骨盆参数之间的关系。因此，我们将体重指数 (BMI)、SVA、TK 和 PI-LL 的值输入多元回归模型，以调整潜在的混杂因素。 SVA、TK和PT随着年龄的增长而增加，LL随着年龄的增长而减少。关于性别差异，男性的 TK 在统计学上显着大于女性，而男性的 LL、PT 和 PI 在统计学上显着小于女性。 SVA与TK之间、SVA与PI-LL之间以及TK与PI-LL之间的相关系数分别为无相关、强相关和弱相关。年龄与脊柱骨盆参数之间的多元回归分析结果显示，男性SVA、TK和PI-LL的标准化偏回归系数分别为0.17、0.30和0.23，女性分别为0.29、0.32和0.23。我们发现所有参数都与男性和女性的年龄显着相关。 SVA、TK和PT随着年龄的增长而增加，LL随着年龄的增长而减少。多元回归分析结果还表明，SVA、TK和PI-LL与年龄相关。事实上，PI-LL 值随着年龄的增长而增加。在这项研究中，显示了更严重的 PI-LL 不匹配，表明脊柱排列不良的风险增加。各性别脊柱骨盆参数的绝对值差异很小，但具有统计学意义。因此，应该进行进一步的研究来证实这一发现。
To establish the normal values of spino-pelvic alignment and to clarify the effect of age-related changes using large, community-based cohorts. In this study, data from 1461 participants (466 men, 995 women) were analyzed. On lateral standing radiographs, the following parameters were measured: thoracic kyphosis (TK), lumbar lordosis (LL), pelvic tilt (PT), pelvic incidence (PI), and C7 sagittal vertical axis (SVA). All values are expressed as the mean±standard deviation. The Spearman rank correlation coefficient was used to examine correlations between variables of spino-pelvic parameters. Finally, we analyzed the relationship between age and spino-pelvic parameters. Therefore, we entered values for the body mass index (BMI), SVA, TK, and PI-LL into a multiple regression model to adjust for potential confounding factors. The SVA, TK, and PT increased with age, and LL decreased with age. Regarding sex differences, the TK was statistically significantly larger in men than in women, and LL, PT, and PI were statistically significantly smaller in men than in women. Correlation coefficients between the SVA and TK, between the SVA and PI-LL, and between TK and PI-LL were none, strong, and weak, respectively. Results of multiple regression analysis between age and spino-pelvic parameters showed that the standardized partial regression coefficients for the SVA, TK, and PI-LL were 0.17, 0.30, and 0.23, respectively, in men and 0.29, 0.32, and 0.23, respectively, in women. We found that all parameters were significantly associated with age in men and women. The SVA, TK, and PT increased with age, and LL decreased with age. Results of multiple regression analysis also demonstrated that the SVA, TK, and PI-LL are related to age. Indeed, the PI-LL value increased with age. In this study, a more excessive PI-LL mismatch was shown, indicating an increased risk of spinal malalignment. Differences in the absolute values of spino-pelvic parameters in each sex were small yet statistically significant. Thus, further study should be performed to corroborate this finding.