A joint analysis of asthma affection status and IgE levels in multiple data sets collected for asthma.
A joint analysis of asthma affection status and IgE levels in multiple data sets collected for asthma.
复制标题
对收集的多个哮喘数据集中的哮喘患病状况和 IgE 水平进行联合分析。
DOI:
10.1002/gepi.2001.21.s1.s148
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发表时间:
2001
期刊:
影响因子:
--
通讯作者:
Kruglyak,L
中科院分区:
文献类型:
--
作者:
Markianos,K;Carlson,S;Gibbs,M;Kruglyak,L
We present a joint linkage analysis of eight data sets collected for asthma. Three of the data sets are full genome scans, while the remaining five concentrate on a 40‐cM region on chromosome 5. We perform the analysis using one qualitative and one quantitative phenotype: asthma status and IgE level. Considering all data sets simultaneously, we do not find evidence for linkage to asthma affection status beyond the level expected to occur by chance twice per genome scan. In contrast, we observe significant linkage to IgE level on chromosome 6. © 2001 Wiley‐Liss, Inc.