A freely accessible, evidence based, objective system of analysis of posterior capsular opacification; evidence for its validity and reliability.
A freely accessible, evidence based, objective system of analysis of posterior capsular opacification; evidence for its validity and reliability.
复制标题
一个自由访问的，基于证据的，客观的后囊分析系统；证据证明其有效性和可靠性。
DOI：
10.1186/1471-2415-5-9
复制
发表时间：
2005-04-07
影响因子：
2
通讯作者：
中科院分区：
文献类型：
--
作者：
本研究的目的是开发一种基于证据、客观且免费的后囊膜混浊（PCO）数字图像的计算机化分析系统。本文将为所开发系统的可靠性和有效性提供证据。考虑到目前发表的关于PCO视觉意义的证据和对PCO图像的额外调查分析，开发了PCO分析系统。讨论了图像处理和分析步骤的细节，并描述了测量接近中心区域加权熵分数的最终系统。为了评估有效性，评估了系统测量PCO进展的能力以及其最终计算机化分数的视觉意义。对系统的可靠性进行了评估。最后的系统运行成功，操作简单。对PCO的分析表明，该系统能够检测PCO的早期进展，以及检测视觉上显著的PCO。没有临床PCO的图像在分析中得分很低。分析系统的可靠性令人满意。本文提出了一种基于证据的、客观的、临床有用的PCO分析系统。为其有效性和可靠性提供了大量证据。
The aim of this study was to develop a system of computerised analysis of digital images of posterior capsule opacification (PCO) that is evidence based, objective and freely available. The paper will present evidence for the reliability and validity of the developed system. The system of PCO analysis was developed considering current published evidence on visual significance of PCO and additional investigative analysis of PCO images. Details of the image processing and analysis steps are discussed and a final system that measures an entropy score weighted toward proximity to central areas is described. In order to assess validity, the systems ability to measure PCO progression is assessed along with the visual significance of its final computerised scores. Reliability of the system is also assessed. The final system runs successfully and is simple to use. Analyses of PCO by the system show an ability to detect early progression of PCO as well as detection of visually significant PCO. Images with no clinical PCO produce very low scores in the analysis. Reliability of the system of analysis is shown to be satisfactory. This paper presents a system of PCO analysis that is evidence based, objective and clinically useful. Substantial evidence is provided for its validity and reliability.