Contribution of the 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography to the diagnosis of primary osseous Hodgkin lymphoma.
Contribution of the 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography to the diagnosis of primary osseous Hodgkin lymphoma.
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DOI：
10.1136/bcr.08.2008.0696
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发表时间：
2009-01-01
期刊：
影响因子：
0.9
通讯作者：
Gomez-Brouchet, Anne
中科院分区：
文献类型：
--
作者：
Breibach, Florence;Julian, Anne;Gomez-Brouchet, Anne
霍奇金淋巴瘤通常表现为淋巴结病变，很少累及淋巴结外部位。尽管先前已有原发性结外霍奇金淋巴瘤病例的报道，但该疾病的原始性质的现实很难用传统的高分辨率成像技术（例如计算机断层扫描或磁共振成像）来验证，因为它们无法评估该疾病在整个身体中的扩散。我们在此报告一例原发性骨性霍奇金淋巴瘤病例，由于新成像技术 2-[18F]-氟-2-脱氧-d-葡萄糖正电子发射断层扫描/计算机断层扫描 (18F-FDG-PET/CT) 的重要贡献，该病例被视为 I 期结外 IE。 PET 能够将继发性骨侵犯的系统性霍奇金淋巴瘤与原始骨性霍奇金淋巴瘤区分开来。该技术在展示肿瘤的孤立骨定位方面具有高度特异性，应推荐用于所有假定的骨淋巴瘤患者。
Hodgkin lymphoma typically presents as a nodal lesion and infrequently involves extra nodal sites. Although cases of primary extra-nodal Hodgkin lymphoma have been reported previously, the reality of the primitive nature of the disease was difficult to authenticate with traditional high resolution imaging techniques, such as computed tomography or magnetic resonance imaging, because they cannot evaluate the spread of the disease throughout the whole body. We report here a case of primary osseous Hodgkin lymphoma, regarded as stage I extranodal IE thanks to the important contribution of a new imaging technique, the 2-[18F]-fluoro-2-deoxy-d-glucose positron emission tomography/ computed tomography (18F-FDG-PET/CT). PET enables systemic Hodgkin lymphoma with secondary bone invasion to be distinguished from primitive osseous Hodgkin lymphoma. This technique is highly specific in demonstrating the isolated osseous localisation of the tumour and should be recommended in all patients with putative osseous lymphoma.