Longitudinal Network Stability of the Functional Impairment of Anxiety and Depression
Longitudinal Network Stability of the Functional Impairment of Anxiety and Depression
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DOI：
10.1177/2167702617745640
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发表时间：
2018-05-01
影响因子：
4.8
通讯作者：
Hofmann, Stefan G.
中科院分区：
文献类型：
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作者：
Curtiss, Joshua;Ito, Masaya;Hofmann, Stefan G.
焦虑和抑郁是伴有显著功能损害的共病。本研究探讨了与焦虑和抑郁相关的功能障碍网络结构的时间变化。来自日本的临床样本（n = 1，667）完成了一系列自我报告工具，以评估焦虑和抑郁障碍的程度和水平。使用偏相关系数和glasso正则化程序在两个时间点估计网络结构。进行了几次排列测试，以检查网络随时间的变化。随着时间的推移，网络的全局和个体特征保持稳定。此外，在这两个时间点，抑郁比焦虑更重要。结果应根据涉及日本样本的文化因素进行解释。这些结果强调了焦虑和抑郁的功能损害的时间稳定性以及抑郁在整个共病网络中的重要性。
Anxiety and depression are comorbid conditions with significant functional impairment. This study examines the temporal changes in the network structure of the functional impairment associated with anxiety and depression. A clinical sample (n = 1,667) of individuals from Japan completed a battery of self-report instruments to assess the degree and level of impairment of anxiety and depression. The network structure was estimated at two time points using partial correlation coefficients and the glasso regularization procedure. Several permutation tests were conducted to examine network changes over time. Global and individual features of the network were stable across time. Furthermore, depression was more central than anxiety at both time points. Results should be interpreted in light of cultural factors involving the Japanese sample. These results underscore the temporal stability of the functional impairment of anxiety and depression as well as the importance of depression in the overall comorbid network.