Imaging
Imaging
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DOI：
10.1007/978-3-030-67175-4_10
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发表时间：
2021
期刊：
影响因子：
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通讯作者：
F. Alibaz-Oner;Haner Direskeneli
中科院分区：
文献类型：
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作者：
F. Alibaz-Oner;Haner Direskeneli
传统的数字减影血管造影(DSA)曾是诊断TAK的“金标准”。然而，磁共振血管成像已经成为诊断TAK的最首选的成像工具，并被建议作为EULAR最近的LVV成像指南的首选方法。CT血管造影术也是一种廉价而快速的工具，有助于确定与血管狭窄和闭塞相关的损害。FDG-PET-CT检测18-F-FDG的血管分布，评估主动脉及其主要分支的代谢活动，通常是炎症活动，并在TAK患者的临床病程中显示闭塞或动脉瘤形成之前的早期血管变化。最后，超声多普勒增强检查有助于颈动脉病变的诊断。成像在评估疾病活动性方面的作用目前是一个很有前途的研究领域，特别是在治疗性临床试验中。
Conventional digital subtraction angiography (DSA) used to be the “gold standard” for the diagnosis of TAK. However, MR angiography has become the most preferred imaging tool for the diagnosis of TAK and is suggested to be the first-choice of modality in recent EULAR guidelines for imaging in LVV. CT angiography is also helpful as a cheap and fast tool to determine the damage associated with vascular stenosis and occlusion. FDG-PET-CT, detecting the vascular distribution of 18-F-FDG, assesses the metabolic, usually inflammatory activity in aorta and its major branches and demonstrate early vascular changes before occlusions or aneursym development during the clinical course of TAK patients. Finally, Doppler US with contrast enhancement is helpful for carotid lesions. The role of imaging to evaluate disease activity is currently an area of promising research, especially for therapeutic clinical trials.