Fine particle mass from the Diskus inhaler and Turbuhaler inhaler in children with asthma
Fine particle mass from the Diskus inhaler and Turbuhaler inhaler in children with asthma
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DOI：
10.1183/09031936.98.11051111
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发表时间：
1998-05-01
影响因子：
24.3
通讯作者：
Burnell, PKP
中科院分区：
文献类型：
--
作者：
Bisgaard, H;Klug, B;Burnell, PKP
为研究吸入剂的剂量一致性和微粒分布，对18例4岁和18例8岁哮喘儿童分别进行吸入剂的吸入压力-时间曲线的测定，并将测定的数据用于吸入压力-时间曲线模拟器，以评价吸入剂的释药效果。特别是评估在粗颗粒（>4.7 μ m）和细颗粒（4.7 μ m）、细颗粒（
The study aimed to investigate dose consistency and particle distribution from the dry powder inhalers Diskus and Turbuhaler.Full profiles of inhalation pressure versus time were recorded in 18 4 gr old and 18 8 yr old asthmatic children through Diskus and Turbuhaler inhalers, These data mere used in an inhalation profile simulator to assess drug delivery from both a Diskus inhaler and a Turbuhaler inhaler, and in particular to assess the proportion of drug emitted in the coarse (>4.7 mu m) and fine (4.7 mu m), fine particles (