DEGseq: an R package for identifying differentially expressed genes from RNA-seq data
DEGseq: an R package for identifying differentially expressed genes from RNA-seq data
复制标题
DEGseq：一个 R 包，用于从 RNA-seq 数据中识别差异表达基因
DOI：
10.1093/bioinformatics/btp612
复制
发表时间：
2010-01-01
期刊：
影响因子：
5.8
通讯作者：
Zhang, Xuegong
中科院分区：
文献类型：
--
作者：
Wang, Likun;Feng, Zhixing;Zhang, Xuegong
总结
高通量RNA测序（RNA-seq）正迅速成为主要的定量转录组分析平台。在这里，我们提出了DEGseq，一个R软件包，用于识别来自不同样本的RNA-seq数据的差异表达基因或亚型。在这个软件包中，我们集成了现有的三种方法，并介绍了两种新的方法，基于MA图检测和可视化基因表达差异。
可用性
可以在http://bioinfo.au.tsinghua.edu.cn/software/degseq上获得R包和快速入门小插图
SUMMARY
High-throughput RNA sequencing (RNA-seq) is rapidly emerging as a major quantitative transcriptome profiling platform. Here, we present DEGseq, an R package to identify differentially expressed genes or isoforms for RNA-seq data from different samples. In this package, we integrated three existing methods, and introduced two novel methods based on MA-plot to detect and visualize gene expression difference.
AVAILABILITY
The R package and a quick-start vignette is available at http://bioinfo.au.tsinghua.edu.cn/software/degseq