Estimating child mortality due to diarrhoea in developing countries
Estimating child mortality due to diarrhoea in developing countries
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DOI：
10.2471/blt.07.050054
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发表时间：
2008-09-01
期刊：
影响因子：
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通讯作者：
Shibuya, Kenji
中科院分区：
文献类型：
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作者：
Boschi-Pinto, Cynthia;Velebit, Lana;Shibuya, Kenji
目的应用儿童健康流行病学参考小组(CHERG)标准，对国家、地区和全球范围内的腹泻死亡率进行估算。收集了关于每项研究及其人群的特征的信息。使用回归模型将这些特征与腹泻死亡率比例联系起来，并预测其在全国人口中的分布。全球5岁以下儿童腹泻死亡人数估计为187万人(95%可信区间，CI：1.56-2.19)，约占儿童总死亡人数的19%。世卫组织非洲和东南亚地区占发展中国家儿童腹泻死亡总数的78%(14.6亿)；其中73%集中在15个发展中国家。结论由于缺乏定期生成死因信息的系统，阻碍了控制腹泻死亡和降低5岁以下儿童死亡率的干预措施的规划和评估。这里使用的方法提供了国家一级的估计数，这些估计数构成了在没有足够数据的情况下进行规划的替代信息。
Objective The major objective of this study is to provide estimates of diarrhoea mortality at country, regional and global level by employing the Child Health Epidemiology Reference Group (CHERG) standard.Methods A systematic and comprehensive literature review was undertaken of all studies published since 1980 reporting under-5 diarrhoea mortality. Information was collected on characteristics of each study and its population. A regression model was used to relate these characteristics to proportional mortality from diarrhoea and to predict its distribution in national populations.Findings Global deaths from diarrhoea of children aged less than 5 years were estimated at 1.87 million (95% confidence interval, Cl: 1.56-2.19), approximately 19% of total child deaths. WHO African and South-East Asia Regions combined contain 78% (1,46 million) of all diarrhoea deaths occurring among children in the developing world; 73% of these deaths are concentrated in just 15 developing countries.Conclusion Planning and evaluation of interventions to control diarrhoea deaths and to reduce under-5 mortality is obstructed by the lack of a system that regularly generates cause-of-death information. The methods used here provide country-level estimates that constitute alternative information for planning in settings without adequate data.