Clinical validation and guidelines for the SCORAD index: Consensus report of the European task force on atopic dermatitis
Clinical validation and guidelines for the SCORAD index: Consensus report of the European task force on atopic dermatitis
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DOI：
10.1159/000245677
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发表时间：
1997-01-01
期刊：
影响因子：
3.4
通讯作者：
Taieb, A
中科院分区：
文献类型：
--
作者：
Kunz, B;Oranje, AP;Taieb, A
背景资料：我们以前曾报道过SCORAD指数是如何设计的，这个累积指数结合了客观（病变的范围和强度）和主观（白天瘙痒和睡眠丧失）标准，目的：研究客观SCORAD标准评分的观察者间变异性，并优化评分指南，材料和方法：1993-1994年在汉堡、波尔多和鹿特丹组织了三次评分会议，共计19名患者（14名儿童和5名成人）和23名医生，其中12人至少参加了2次评分会议;使用SCORAD File Marker Pro软件处理了169份评估表。在每次治疗中，拍摄每位患者的全身照片和特写视图，并在最终评价时对这些材料进行审查，结果：根据9分规则，病变程度显示观察者间变异性，大多数患者的病变强度为中度，累及体表面积的20-60%，强度项目评分总体上更一致，但变化消退，特别是渗出/结痂和地衣化，注意到低分和高分的情况以及培训的好处，结论：这项研究允许使用SCORAD系统优化临床评分，已提出一项建议，根据客观标准对特应性皮炎的严重程度进行分级，分为三组进行临床试验。SCORAD指数仍然是试验随访的主要标准。
Background: We have previously reported how-the SCORAD index was designed, This cumulative index combines objective (extent and intensity of lesions) and subjective (daytime pruritus and sleep loss) criteria, Aims: To study interobserver variability in scoring for objective SCORAD criteria and to optimize the scoring guidelines, Material and Methods: Three scoring sessions were organized in 1993-1994 in Hamburg, Bordeaux and Rotterdam totalizing 19 patients (14 children and 5 adults) and 23 physicians, among whom 12 participated in at least 2 scoring sessions; 169 evaluation sheets have been processed using the SCORAD File Marker Pro software. at each session, total body photographs and close-up views were taken of each patient, and this material was reviewed at the final evaluation, Results: The extent of lesions according to the rule of nines showed interobserver variability mostly for patients with lesions of moderate intensity involving 20-60% of body surface, Intensity items were scored with more consistency overall, but variations subsided especially for oozing/crusts and lichenifications, Low and high scorer profiles and the benefit of training were noted, Conclusions: This study has allowed to optimize clinical scoring using the SCORAD system, A proposal has been made to grade the severity of atopic dermatitis according to objective criteria in three groups for inclusion in clinical trials. The SCORAD index remains the major criterion for follow-up in trials.