Myocyte renewal and ventricular remodelling

Myocyte renewal and ventricular remodelling
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DOI:
10.1038/415240a
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发表时间:
2002-01-10
期刊:
影响因子:
64.8
通讯作者:
Nadal-Ginard, B
Nadal-Ginard, B
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Anversa, P;Nadal-Ginard, B

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保持年轻的心态是一个令人向往但难以实现的目标。然而,我们不知道的是,肌细胞再生可以做到这一点。在成人心肌中持续的细胞更新被认为是不可能的,但是多能性心脏干细胞可能能够更新心肌,并且在某些情况下,可以被诱导修复梗死后破碎的心脏。
Remaining young at heart is a desirable but elusive goal. Unbeknown to us, however, myocyte regeneration may accomplish just that. Continuous cell renewal in the adult myocardium was thought to be impossible, but multipotent cardiac stem cells may be able to renew the myocardium and, under certain circumstances, can be coaxed to repair the broken heart after infarction.